{"id":"W2125686345","doi":"10.1093/glycob/cwm081","title":"Affinities of Shiga toxins 1 and 2 for univalent and oligovalent Pk-trisaccharide analogs measured by electrospray ionization mass spectrometry","year":2007,"lang":"en","type":"article","venue":"Glycobiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Glycomics Centre","keywords":"Chemistry; Trisaccharide; Affinities; Electrospray ionization; Mass spectrometry; Binding site; Stereochemistry; Binding affinities; Ligand (biochemistry); Glycolipid; Biochemistry; Chromatography; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002250148,0.0003529278,0.0002529062,0.0001963258,0.0001424184,0.0003183153,0.0002455192,0.000433397,0.002552558],"category_scores_gemma":[0.0004489325,0.0001581886,0.0001362188,0.0001960095,0.0001959465,0.0002229614,0.0001879336,0.0003493475,0.0003999645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004443763,"about_ca_system_score_gemma":0.0001741899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009141032,"about_ca_topic_score_gemma":0.001122225,"domain_scores_codex":[0.9997243,0.00003883717,0.00001383694,0.00005501953,0.0001223861,0.00004558313],"domain_scores_gemma":[0.9998453,0.00006061048,0.00002428711,0.000008612757,0.00002822033,0.00003290467],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008801922,0.00001135165,0.0004421524,0.00001749816,0.00000519543,0.00001383811,0.00001127064,0.0001639722,0.9984231,0.00004774909,0.00002325175,0.0007524549],"study_design_scores_gemma":[0.00001991302,0.0002623611,0.01038316,0.000006547488,0.00001167816,0.000161801,0.00004428489,0.002579761,0.9854029,0.00007788288,0.001039031,0.00001056264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948322,0.0007720303,0.002705099,0.00006328761,0.00001044848,0.00001721697,0.0001821718,0.00003555297,0.001381932],"genre_scores_gemma":[0.9921749,0.0005198114,0.00363236,0.0001650569,0.000008179776,0.00004710432,0.0005682437,0.00001425532,0.002870128],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002552558,"threshold_uncertainty_score":0.0085392,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01398811510277508,"score_gpt":0.2751065700429181,"score_spread":0.261118454940143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}