{"id":"W2125686345","doi":"10.1093/glycob/cwm081","title":"Affinities of Shiga toxins 1 and 2 for univalent and oligovalent Pk-trisaccharide analogs measured by electrospray ionization mass spectrometry","year":2007,"lang":"en","type":"article","venue":"Glycobiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Glycomics Centre","keywords":"Chemistry; Trisaccharide; Affinities; Electrospray ionization; Mass spectrometry; Binding site; Stereochemistry; Binding affinities; Ligand (biochemistry); Glycolipid; Biochemistry; Chromatography; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005267136,0.0001523536,0.0002374922,0.00008915611,0.00009152566,0.000009775468,0.0001064308,0.000175266,0.000004709601],"category_scores_gemma":[0.00035538,0.0001399959,0.00004522756,0.0001291523,0.0002683219,0.000004323779,0.00009731758,0.00008630649,3.258501e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002664276,"about_ca_system_score_gemma":0.00005525812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001868901,"about_ca_topic_score_gemma":0.00007684938,"domain_scores_codex":[0.9989049,0.00006617119,0.0002328337,0.0003297878,0.00008827176,0.0003780643],"domain_scores_gemma":[0.9993972,0.00009781712,0.0001037944,0.0001620444,0.0001654397,0.00007369197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003109892,0.00004065449,0.01236517,0.00005193863,0.0001260632,8.870701e-7,0.00004328142,0.000001076681,0.9846849,0.0007980927,0.00104905,0.0005279341],"study_design_scores_gemma":[0.001243029,0.001909556,0.01908953,0.00001167975,0.0000470024,0.00001804446,0.0002797624,0.00003047637,0.963679,0.0005894972,0.01284891,0.0002535372],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9739419,0.006749601,0.01828744,0.0002279577,0.00008473486,0.0003216956,0.00008879732,0.00001113289,0.00028675],"genre_scores_gemma":[0.9933328,0.003635006,0.002446843,0.000103298,0.0001102096,0.00001550197,0.0001210965,0.00001543297,0.0002197975],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0210059,"threshold_uncertainty_score":0.5708868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01398811510277508,"score_gpt":0.2751065700429181,"score_spread":0.261118454940143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}