{"id":"W2125753995","doi":"10.1128/mcb.23.13.4586-4597.2003","title":"The Murine Nck SH2/SH3 Adaptors Are Important for the Development of Mesoderm-Derived Embryonic Structures and for Regulating the Cellular Actin Network","year":2003,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":187,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Ontario Institute for Cancer Research; University of Toronto; Mount Sinai Hospital","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Biology; Cell biology; Embryonic stem cell; Signal transducing adaptor protein; Mesoderm; Actin cytoskeleton; Cytoskeleton; Genetics; Cell; Gene; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007640502,0.0002546446,0.0002404483,0.00002089501,0.0008666836,0.00004528558,0.0002458446,0.000186285,0.000006103649],"category_scores_gemma":[0.0001952723,0.0001434084,0.0001737151,0.0000707388,0.0001943092,0.000003313799,0.0001363288,0.0001342764,1.605467e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001024468,"about_ca_system_score_gemma":0.0000892269,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008002535,"about_ca_topic_score_gemma":0.00008865481,"domain_scores_codex":[0.998499,0.0001519061,0.0004301499,0.0004195915,0.00008265338,0.0004167508],"domain_scores_gemma":[0.9988596,0.0001742104,0.0003242268,0.0004615816,0.0001172378,0.00006312835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009771179,0.00001907584,0.000122769,0.00002589049,0.0002644807,6.503804e-7,0.00008636028,0.00007014571,0.9845203,0.01243856,0.0001876519,0.002166376],"study_design_scores_gemma":[0.0005250668,0.0002236515,0.00007568068,0.00001077667,0.00009353594,0.00001325097,0.0005957523,0.0009369548,0.8509945,0.003025046,0.1433083,0.0001974692],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8199863,0.02110288,0.1568455,0.000532157,0.0004140495,0.001025087,0.00002187665,0.000008151537,0.0000639823],"genre_scores_gemma":[0.996218,0.0003979727,0.002595182,0.0001548554,0.0001237857,0.0001675481,0.0001090869,0.00003752363,0.0001960988],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1762316,"threshold_uncertainty_score":0.6665917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01167615387444391,"score_gpt":0.2418934615973132,"score_spread":0.2302173077228693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}