{"id":"W2125806073","doi":"10.1093/ndt/gfm365","title":"High glucose induces macrophage inflammatory protein-3  in renal proximal tubule cells via a transforming growth factor- 1 dependent mechanism","year":2007,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"Chronic Kidney Disease and Diabetes","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"National Health and Medical Research Council; Medical Research Council","keywords":"Medicine; Chemokine; Inflammation; Transforming growth factor; Pathogenesis; Diabetic nephropathy; Fibrosis; Nephropathy; Macrophage; Kidney; Internal medicine; Growth factor; Diabetes mellitus; Transforming growth factor beta; Endocrinology; Immunology; Receptor; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001299985,0.0003274107,0.0003159976,0.0002267107,0.0001863124,0.0002731443,0.0001423894,0.0002337462,0.001516108],"category_scores_gemma":[0.0000829124,0.000146924,0.0004619472,0.0002515911,0.0002600786,0.0001228894,0.0001721382,0.0006527795,0.0003670583],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003234954,"about_ca_system_score_gemma":0.0002542628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001062389,"about_ca_topic_score_gemma":0.00121157,"domain_scores_codex":[0.9998306,0.00002782329,0.0000109253,0.00001694115,0.00005678431,0.00005686944],"domain_scores_gemma":[0.9999008,0.00001346398,0.00002757734,0.00001110125,0.00001701346,0.00003004933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004969261,0.0001287613,0.0005952888,0.00009239299,0.00001227489,0.0001897358,0.00002466751,0.00004762573,0.9975919,0.00004018475,0.00009618609,0.0006840542],"study_design_scores_gemma":[0.0001793343,0.001496835,0.06024574,0.00001912392,0.0000747626,0.0007402916,0.0002295732,0.001258032,0.9329137,0.0001464234,0.00268068,0.00001549763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950331,0.00184625,0.001395514,0.0001818753,0.00006872871,0.0000345858,0.0003109616,0.00008697822,0.00104207],"genre_scores_gemma":[0.9957516,0.001055005,0.001001214,0.0001551847,0.00003156731,0.00006481555,0.0004331655,0.00001153767,0.001495927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001516108,"threshold_uncertainty_score":0.005071878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006513533191322091,"score_gpt":0.2249472502004991,"score_spread":0.218433717009177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}