{"id":"W2125812952","doi":"10.1242/bio.2011049","title":"Taperin (c9orf75), a mutated gene in nonsyndromic deafness, encodes a vertebrate specific, nuclear localized protein phosphatase one alpha (PP1α) docking protein","year":2011,"lang":"en","type":"article","venue":"Biology Open","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Innovates; Terry Fox Foundation","keywords":"Biology; Protein phosphatase 1; Nuclear protein; Ku70; Stable isotope labeling by amino acids in cell culture; Gene; Molecular biology; Phosphatase; DDB1; DNA damage; Proteome; DNA-binding protein; Protein subunit; Genetics; Cell biology; DNA repair; Proteomics; DNA; Phosphorylation; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004703872,0.0004265934,0.0008279812,0.0001767966,0.0002968014,0.0000696736,0.001033152,0.0005373546,0.004329804],"category_scores_gemma":[0.00004840612,0.0003925052,0.0001123094,0.0002464085,0.0007408069,0.000367781,0.0007584399,0.0004979422,0.001576432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007921854,"about_ca_system_score_gemma":0.0001506136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005953485,"about_ca_topic_score_gemma":0.0004989182,"domain_scores_codex":[0.997212,0.0004977438,0.0006179659,0.0008118585,0.00002940187,0.0008310226],"domain_scores_gemma":[0.9990631,0.00003204608,0.0002710866,0.000522771,0.00005650535,0.00005450566],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001979553,0.0005197035,0.0008891631,0.00002917017,0.0002009789,0.0001116984,0.0005505661,0.000001471988,0.9856724,0.006744299,0.0005429402,0.002758092],"study_design_scores_gemma":[0.005154983,0.0006301603,0.001749307,0.0003060885,0.00003160188,0.0001390548,0.0003320945,0.00001998848,0.9707266,0.001451974,0.01871948,0.0007386834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937261,0.001368405,0.0001180786,0.0001466529,0.0002358406,0.002414893,0.0002016971,0.0001200307,0.001668299],"genre_scores_gemma":[0.9944844,0.0001231095,0.003064132,0.0002659032,0.00002464411,0.0002698304,0.0003322125,0.00006370163,0.001372127],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01817654,"threshold_uncertainty_score":0.9998527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04287584319512892,"score_gpt":0.2416797123754131,"score_spread":0.1988038691802842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}