{"id":"W2125812952","doi":"10.1242/bio.2011049","title":"Taperin (c9orf75), a mutated gene in nonsyndromic deafness, encodes a vertebrate specific, nuclear localized protein phosphatase one alpha (PP1α) docking protein","year":2011,"lang":"en","type":"article","venue":"Biology Open","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Innovates; Terry Fox Foundation","keywords":"Biology; Protein phosphatase 1; Nuclear protein; Ku70; Stable isotope labeling by amino acids in cell culture; Gene; Molecular biology; Phosphatase; DDB1; DNA damage; Proteome; DNA-binding protein; Protein subunit; Genetics; Cell biology; DNA repair; Proteomics; DNA; Phosphorylation; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007069851,0.0009139137,0.0002745973,0.0006208231,0.0003511837,0.0002658303,0.0002901996,0.0006111448,0.001828927],"category_scores_gemma":[0.0001929738,0.0001125911,0.0004358821,0.0002971123,0.0003930722,0.0001324948,0.0002824838,0.0004255078,0.0006800924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003880831,"about_ca_system_score_gemma":0.0002422003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001493854,"about_ca_topic_score_gemma":0.002070235,"domain_scores_codex":[0.9998763,0.00000799378,0.00001388608,0.00004757487,0.00004086051,0.00001341019],"domain_scores_gemma":[0.9998771,0.00001698576,0.00006521244,0.000005716063,0.000006989308,0.00002793104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000161974,0.00002595789,0.002855221,0.00008365681,0.00004898626,0.01213473,0.00006086371,0.0002697903,0.9744368,0.0004808785,0.0003781654,0.009062934],"study_design_scores_gemma":[0.00007010004,0.0004332081,0.1651484,0.00008377388,0.0002390728,0.08243357,0.0002051275,0.003194861,0.7249141,0.0006725411,0.02251943,0.00008572356],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873268,0.001289733,0.006559046,0.0001493319,0.0001093781,0.00004302551,0.002172735,0.0003086872,0.002041234],"genre_scores_gemma":[0.9905533,0.0005617027,0.003833235,0.00008793524,0.00002521401,0.00002577045,0.001969377,0.00003160851,0.002911937],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001828927,"threshold_uncertainty_score":0.006118417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04287584319512892,"score_gpt":0.2416797123754131,"score_spread":0.1988038691802842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}