{"id":"W2125817955","doi":"10.1093/humrep/deh158","title":"Time-dependent capability of human oocytes for activation and pronuclear formation during metaphase II arrest","year":2004,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"Abbott Laboratories","keywords":"Pronucleus; Oocyte; Andrology; Blastomere; Polar body; Human fertilization; Oocyte activation; Metaphase; Meiosis; Embryo; Biology; In vivo; Embryogenesis; Meiosis II; Genetics; Medicine; Chromosome; Zygote; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009780425,0.0001227663,0.0002513549,0.0001001779,0.0004372316,0.000006517169,0.00003603018,0.00009636764,0.00002443191],"category_scores_gemma":[0.0004642394,0.0001104495,0.00006826815,0.00007974538,0.0002317616,0.0002760605,0.00003253308,0.0001269195,0.000002523762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000139857,"about_ca_system_score_gemma":0.00002080367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004105824,"about_ca_topic_score_gemma":0.000007818465,"domain_scores_codex":[0.9987015,0.00006071772,0.0003816765,0.0005943538,0.0001248353,0.0001369027],"domain_scores_gemma":[0.9989279,0.00001071911,0.0002204937,0.0005551184,0.0002411701,0.00004462304],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001439971,0.0004295679,0.001075843,0.0003984587,0.00004550418,3.14798e-7,0.001080193,0.00004399284,0.9942189,0.0002248462,0.00001337896,0.001029024],"study_design_scores_gemma":[0.001361255,0.0006463949,0.2358568,0.00004224456,0.00007135629,0.00002110848,0.0001478235,0.00001069803,0.7590305,0.002640335,0.00008805523,0.00008344476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976197,0.00008640141,0.0001636606,0.0004955927,0.0001085138,0.001317208,0.000003882171,0.00008069556,0.0001243702],"genre_scores_gemma":[0.9988428,0.000004896666,0.0002145923,0.000008146495,0.0003332313,0.00006332035,0.00007606261,0.00001339995,0.0004435614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2351884,"threshold_uncertainty_score":0.4503999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03039437765645696,"score_gpt":0.2971303857712962,"score_spread":0.2667360081148393,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}