{"id":"W2125818518","doi":"10.1261/rna.768207","title":"Determinants of targeting by endogenous and exogenous microRNAs and siRNAs","year":2007,"lang":"en","type":"article","venue":"RNA","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":387,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Knut och Alice Wallenbergs Stiftelse","keywords":"Biology; microRNA; Small interfering RNA; Psychological repression; Endogeny; Messenger RNA; RNA; Genetics; Computational biology; Cell biology; Gene expression; Gene; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000410377,0.0002219357,0.0002783561,0.0001891102,0.00008579063,0.000482664,0.0001682563,0.0002216302,0.0008458042],"category_scores_gemma":[0.0006419105,0.0002258117,0.000196293,0.0001247249,0.0003223252,0.000175766,0.0002433106,0.0003578303,0.0003714591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002965519,"about_ca_system_score_gemma":0.0002114204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001521318,"about_ca_topic_score_gemma":0.0002846856,"domain_scores_codex":[0.9992256,0.0001748015,0.00007354088,0.0001793106,0.0002548518,0.00009187772],"domain_scores_gemma":[0.9995224,0.0001763376,0.0001313797,0.0000560446,0.00005098866,0.00006275595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005278136,0.000007522975,0.0004075828,0.00001460013,0.000002863094,0.00001754435,0.000004444315,0.00005902258,0.998569,0.0000810739,0.000008967445,0.0007746199],"study_design_scores_gemma":[0.000005257929,0.0001323437,0.005822887,0.000002265336,0.00001187094,0.0001283321,0.00001129404,0.001540721,0.9915178,0.00004769215,0.0007762864,0.000003236568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863583,0.001157182,0.0104318,0.00005182403,0.00002550266,0.00003343192,0.0002036338,0.000111074,0.001627281],"genre_scores_gemma":[0.9946814,0.0002597714,0.004003866,0.0000353391,0.000008132605,0.00004061435,0.0002667862,0.00003435504,0.0006697078],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008458042,"threshold_uncertainty_score":0.002829432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00935275417377023,"score_gpt":0.2345180007239736,"score_spread":0.2251652465502034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}