{"id":"W2125833216","doi":"10.1210/en.2009-0803","title":"Critical Roles of Kisspeptins in Female Puberty and Preovulatory Gonadotropin Surges as Revealed by a Novel Antagonist","year":2009,"lang":"en","type":"article","venue":"Endocrinology","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":215,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Medical Research Council","keywords":"Endocrinology; Internal medicine; Gonadotropin; Antagonist; In vivo; Systemic administration; Ovary; Medicine; Hormone; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005714224,0.000264823,0.0002757945,0.0001202053,0.00009556169,0.0001883734,0.0001471798,0.0001532948,0.00105391],"category_scores_gemma":[0.00006836254,0.00008996448,0.0001611824,0.00006917142,0.0001667105,0.0001851597,0.0001106109,0.0005016683,0.0002225027],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001208697,"about_ca_system_score_gemma":0.0002135063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002015673,"about_ca_topic_score_gemma":0.0004558988,"domain_scores_codex":[0.9999526,0.000005991457,0.000004324,0.00001089707,0.00001249803,0.00001379952],"domain_scores_gemma":[0.9999633,0.000004605821,0.00001310597,0.00000323548,0.000003548014,0.00001221903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002541815,0.00001750492,0.0001165598,0.00003259899,0.000003231038,0.00005249765,0.00000877496,0.00002869723,0.9977689,0.00006142334,0.00001689841,0.001638805],"study_design_scores_gemma":[0.00006691502,0.001852353,0.008208528,0.000008272982,0.00003000114,0.0007689795,0.0000562588,0.0004607938,0.984353,0.000079093,0.004109158,0.000006625712],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940231,0.002495269,0.001885785,0.00008502726,0.00002227742,0.00003408476,0.0003317099,0.00004004062,0.001082571],"genre_scores_gemma":[0.9894965,0.00457152,0.002954213,0.00006915061,0.00002850711,0.00005205386,0.0005077564,0.00001491931,0.002305299],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00105391,"threshold_uncertainty_score":0.003525674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01392264493667064,"score_gpt":0.2935752083009481,"score_spread":0.2796525633642775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}