{"id":"W2125983484","doi":"10.1093/jmicro/dfq002","title":"FGFR3 down-regulates PTH/PTHrP receptor gene expression by mediating JAK/STAT signaling in chondrocytic cell line","year":2010,"lang":"en","type":"article","venue":"Journal of Electron Microscopy","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Transfection; Signal transduction; Receptor; MAPK/ERK pathway; Parathyroid hormone-related protein; Growth hormone receptor; Cell growth; Molecular biology; Biology; Parathyroid hormone; Internal medicine; Cell biology; Endocrinology; Cell culture; Chemistry; Cancer research; Medicine; Calcium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001880087,0.0003691173,0.0002983536,0.0002579617,0.0002706863,0.0003611462,0.0002300654,0.0003119891,0.002164887],"category_scores_gemma":[0.0001369345,0.0001599658,0.0005241083,0.0002417797,0.0002039558,0.0001404903,0.0001642061,0.0007160423,0.0008784842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003749068,"about_ca_system_score_gemma":0.0004027669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002505236,"about_ca_topic_score_gemma":0.00304472,"domain_scores_codex":[0.999674,0.00003585489,0.00003961204,0.00004280151,0.0001247413,0.00008304795],"domain_scores_gemma":[0.9998953,0.00002042058,0.00002281194,0.00001753428,0.00002021766,0.00002372578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004431214,0.00002151656,0.00007272041,0.00002987093,0.000004121039,0.00004010265,0.00001101667,0.0000271735,0.99933,0.00005148836,0.00006046623,0.0003071739],"study_design_scores_gemma":[0.00003985091,0.000240268,0.005328125,0.000007255639,0.00003019783,0.0003899944,0.00004020715,0.001610436,0.9877769,0.00003625229,0.004493171,0.000007445936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856637,0.003417161,0.004337033,0.0003325713,0.0001142786,0.00008452474,0.002112925,0.0002529189,0.00368496],"genre_scores_gemma":[0.9874791,0.001394415,0.003268251,0.0001630736,0.0000258226,0.0000980256,0.002731568,0.0000405475,0.004799269],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002505236,"threshold_uncertainty_score":0.007242322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004576123047513992,"score_gpt":0.2769723275289432,"score_spread":0.2723962044814293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}