{"id":"W2125994231","doi":"10.1021/nl2036047","title":"Remotely Activated Protein-Producing Nanoparticles","year":2012,"lang":"en","type":"article","venue":"Nano Letters","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":113,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Canada's Michael Smith Genome Sciences Centre","funders":"National Institute of Biomedical Imaging and Bioengineering; National Institute of General Medical Sciences; National Cancer Institute","keywords":"Nanotechnology; Nanomaterials; Nanoparticle; Green fluorescent protein; Ribosome; Chemistry; Protein biosynthesis; In vivo; Biophysics; Nanoscopic scale; Translation (biology); Drug delivery; Luciferase; Fluorescence; Materials science; Messenger RNA; Transfection; Biochemistry; Biology; RNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001681457,0.0002433421,0.0001697359,0.0001097603,0.0001172575,0.0002978667,0.0002691846,0.0004656534,0.0007314685],"category_scores_gemma":[0.000205541,0.0001444691,0.0002352771,0.00006464853,0.0002944609,0.0002982703,0.0002278242,0.000433794,0.0004651749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003006714,"about_ca_system_score_gemma":0.0001316196,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001452394,"about_ca_topic_score_gemma":0.0001474132,"domain_scores_codex":[0.9998624,0.00002323547,0.000006885423,0.00005139664,0.00004117994,0.00001489105],"domain_scores_gemma":[0.9999202,0.00002345431,0.00002184444,0.00001231561,0.00001337328,0.000008760666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001384678,0.000007598881,0.00003368238,0.00003365412,0.000002006102,0.00003310229,0.00001380713,0.0002488131,0.9967043,0.001026343,0.00009390514,0.001788954],"study_design_scores_gemma":[0.000006850085,0.00003892706,0.00008710584,0.000002652625,0.000003781606,0.00007108558,0.000003726544,0.001110846,0.9948229,0.0001429567,0.003705393,0.000003753501],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8266509,0.006147554,0.1452905,0.0009677812,0.0003353032,0.0001732573,0.0002815366,0.001166137,0.01898705],"genre_scores_gemma":[0.9437088,0.001493852,0.04676395,0.0002863413,0.00004941269,0.00009242843,0.0001887785,0.0001055163,0.007310844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007314685,"threshold_uncertainty_score":0.002447009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0164314665090457,"score_gpt":0.2731302974584759,"score_spread":0.2566988309494302,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}