{"id":"W2125996889","doi":"10.1161/atvbaha.113.302004","title":"Regulation of ABCA1 Protein Expression and Function in Hepatic and Pancreatic Islet Cells by miR-145","year":2013,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"ABCA1; Glucose homeostasis; Endocrinology; Internal medicine; microRNA; Insulin; Biology; Downregulation and upregulation; Pancreatic islets; Secretion; Chemistry; Islet; Insulin resistance; Transporter; Biochemistry; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002402687,0.0002563973,0.0001976792,0.0001819307,0.0001665032,0.0005136783,0.0001455586,0.0001262158,0.0009063261],"category_scores_gemma":[0.0001724548,0.0001300063,0.0003144182,0.0001377287,0.0001741269,0.0001823828,0.0001694736,0.0003835138,0.000380952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002193985,"about_ca_system_score_gemma":0.0001617752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003438867,"about_ca_topic_score_gemma":0.0004309457,"domain_scores_codex":[0.9998266,0.0000327839,0.00002561835,0.00003779008,0.0000513417,0.00002584788],"domain_scores_gemma":[0.999897,0.0000222217,0.00003284307,0.00001174984,0.00001937013,0.00001667013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001752576,0.00003599266,0.00138575,0.00008273203,0.00001264023,0.00006701946,0.00002625043,0.000078099,0.99353,0.0002098162,0.00007727154,0.004319168],"study_design_scores_gemma":[0.00002049656,0.0002083458,0.01387311,0.00001175295,0.00005624363,0.0002962996,0.00005479846,0.002228797,0.9792091,0.00005373569,0.003981565,0.000005743588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9810915,0.006746206,0.007482001,0.0001333085,0.00007647133,0.00003342174,0.0002336938,0.0001154653,0.00408799],"genre_scores_gemma":[0.9920292,0.001545934,0.004281264,0.00008234961,0.00001566346,0.00003261744,0.000355824,0.00002469351,0.00163253],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009063261,"threshold_uncertainty_score":0.003031909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01391324949811944,"score_gpt":0.2319377348808591,"score_spread":0.2180244853827396,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}