{"id":"W2126015139","doi":"10.1158/0008-5472.can-09-2408","title":"Oncolytic Viral Therapy for Prostate Cancer: Efficacy of Reovirus as a Biological Therapeutic","year":2010,"lang":"en","type":"article","venue":"Cancer Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; Provincial Laboratory of Public Health; Oncolytics Biotech (Canada); Bio-Rad (Canada); University of Calgary; Memorial University of Newfoundland","funders":"","keywords":"Oncolytic virus; Prostate cancer; Cancer research; In vivo; Medicine; Cancer; Apoptosis; Virology; Virus; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002790672,0.0003518296,0.0003907508,0.0003770048,0.0001813346,0.0004661084,0.000248144,0.0003577349,0.001000454],"category_scores_gemma":[0.0001489521,0.00008824214,0.0002990596,0.0001774529,0.0003408878,0.0002545121,0.0002108342,0.0006156191,0.0002038604],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003125631,"about_ca_system_score_gemma":0.0002869824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004876298,"about_ca_topic_score_gemma":0.0008176975,"domain_scores_codex":[0.9998647,0.00003797527,0.000006195988,0.0000202285,0.00003759557,0.00003329265],"domain_scores_gemma":[0.9999222,0.00001724338,0.00001357039,0.00001527038,0.000007722418,0.0000239723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009041923,0.0004845866,0.0008765914,0.0002096613,0.00003889055,0.0001457812,0.00007590222,0.0008459242,0.9525021,0.0007005539,0.0001618265,0.04305394],"study_design_scores_gemma":[0.0002019509,0.01064456,0.006400869,0.00004193959,0.000103161,0.001321264,0.00005048498,0.002056238,0.9670419,0.0002758866,0.01184196,0.00001973434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9601086,0.02583725,0.008538265,0.0003475704,0.00008813324,0.0001344929,0.0001852695,0.0001422908,0.004618138],"genre_scores_gemma":[0.9917583,0.004179149,0.002207366,0.00005419842,0.00002936578,0.00003262141,0.0001355417,0.00001638247,0.001587194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001000454,"threshold_uncertainty_score":0.00334686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08611561862416536,"score_gpt":0.4539950577246943,"score_spread":0.367879439100529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}