{"id":"W2126015139","doi":"10.1158/0008-5472.can-09-2408","title":"Oncolytic Viral Therapy for Prostate Cancer: Efficacy of Reovirus as a Biological Therapeutic","year":2010,"lang":"en","type":"article","venue":"Cancer Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; Provincial Laboratory of Public Health; Oncolytics Biotech (Canada); Bio-Rad (Canada); University of Calgary; Memorial University of Newfoundland","funders":"","keywords":"Oncolytic virus; Prostate cancer; Cancer research; In vivo; Medicine; Cancer; Apoptosis; Virology; Virus; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001503598,0.0002121126,0.0002781159,0.0001519286,0.0002174009,0.00004455326,0.0007413386,0.0002847635,0.0003758444],"category_scores_gemma":[0.0002324329,0.0001660996,0.0001779632,0.0003382949,0.0007196859,0.000005944468,0.0001532821,0.0005886974,0.00002027127],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006768583,"about_ca_system_score_gemma":0.001420921,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004937349,"about_ca_topic_score_gemma":0.0005977072,"domain_scores_codex":[0.9974133,0.0002902765,0.0002899,0.000644932,0.0005115808,0.0008500472],"domain_scores_gemma":[0.9981991,0.0001819673,0.00008052931,0.0007033765,0.0006369846,0.0001980184],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01490977,0.0001979448,0.001355005,0.00002602217,0.0001271287,0.000001881982,0.0001100422,0.00001870459,0.8525551,0.0001071422,0.0007038857,0.1298874],"study_design_scores_gemma":[0.002971771,0.00778398,0.001045955,0.00001893575,0.000005358626,0.00000254337,0.00004197556,0.00002589209,0.9207627,0.0006102292,0.0665269,0.000203792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894775,0.007021067,0.00001341022,0.0009213253,0.0002057587,0.001871553,0.0001212565,0.00001776897,0.0003504179],"genre_scores_gemma":[0.9864254,0.009209392,0.00006532881,0.0002998733,0.0006398128,0.001760421,0.00004503806,0.00006245994,0.001492265],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1296836,"threshold_uncertainty_score":0.6773347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08611561862416536,"score_gpt":0.4539950577246943,"score_spread":0.367879439100529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}