{"id":"W2126040395","doi":"10.1074/jbc.m703370200","title":"UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 Enzymes Are Major Determinants of the Androgen Response in Prostate Cancer LNCaP Cells","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"LNCaP; Prostate cancer; Androgen; Enzyme; Cancer research; Glucuronosyltransferase; Internal medicine; Medicine; Endocrinology; Chemistry; Cancer; Biochemistry; Hormone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009185806,0.0001452532,0.0004220374,0.00004722328,0.00004208262,0.000009048249,0.00013869,0.0001397497,0.00008266179],"category_scores_gemma":[0.0001915547,0.00007208008,0.0001331413,0.0001686039,0.0002787268,0.0000379769,0.00004748925,0.000377418,4.764777e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000113688,"about_ca_system_score_gemma":0.000202278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000148632,"about_ca_topic_score_gemma":0.000008744287,"domain_scores_codex":[0.9987311,0.00007501125,0.0005044683,0.000162702,0.00023549,0.0002912432],"domain_scores_gemma":[0.9990753,0.0002218204,0.0002502145,0.0001389089,0.0001316311,0.000182109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01103034,0.000150658,0.3913643,0.0001334355,0.00003764694,0.0005092207,0.0001187648,0.000001020895,0.5949061,1.643525e-7,0.00005915079,0.001689211],"study_design_scores_gemma":[0.002732989,0.0003814109,0.2263297,0.0003556936,0.00003317571,0.0001887047,0.0002698818,0.000003186698,0.7692593,0.00002022123,0.000358891,0.0000668384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99188,0.007055437,0.000001154652,0.0006869691,0.00005291615,0.0002155484,0.00004313667,0.000003767607,0.00006109085],"genre_scores_gemma":[0.9972236,0.002174177,0.00004785936,0.00007314501,0.00008547949,0.000005016406,0.000001246011,0.000008144288,0.000381326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1743532,"threshold_uncertainty_score":0.293934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02723514354748145,"score_gpt":0.3207942877563825,"score_spread":0.293559144208901,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}