{"id":"W2126048792","doi":"10.1200/jco.2003.03.042","title":"Randomized, Double-Blind, Controlled Trial of Mitoxantrone/Prednisone and Clodronate Versus Mitoxantrone/Prednisone and Placebo in Patients With Hormone-Refractory Prostate Cancer and Pain","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Bone health and treatments","field":"Medicine","cited_by":248,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nova Scotia Cancer Centre","funders":"","keywords":"Medicine; Mitoxantrone; Placebo; Prednisone; Clinical endpoint; Prostate cancer; Internal medicine; Palliative care; Analgesic; Bone pain; Quality of life (healthcare); Randomized controlled trial; Oncology; Surgery; Cancer; Chemotherapy; Anesthesia; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006551161,0.0002974207,0.004096896,0.0002241186,0.00005937057,0.00001254834,0.00005967288,0.000457411,0.0000144676],"category_scores_gemma":[0.00294514,0.0001863433,0.0002281827,0.0001173126,0.0006205842,0.0001625768,0.00003030966,0.0008699955,0.000001034834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001450637,"about_ca_system_score_gemma":0.001572212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001476854,"about_ca_topic_score_gemma":0.0002227262,"domain_scores_codex":[0.9941947,0.001589081,0.003012002,0.0003415439,0.0004423228,0.0004202898],"domain_scores_gemma":[0.9904218,0.005915965,0.002542384,0.0001641551,0.0003328211,0.000622826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9051866,0.00315978,0.06662709,0.00006150618,0.001177648,0.00009114652,0.0001584123,0.000003481244,0.000009951195,0.00003113814,0.0001191999,0.02337405],"study_design_scores_gemma":[0.9267384,0.03650675,0.03277294,0.0001448616,0.001353358,0.00002810898,0.00008841688,0.00006417013,0.000005791806,0.00005184497,0.002104451,0.0001408669],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854192,0.007426224,0.000007682056,0.001927881,0.0007731108,0.004202159,0.00001583757,0.000005723428,0.0002222469],"genre_scores_gemma":[0.9854741,0.01292808,0.000881933,0.0002948847,0.0001618872,0.0001185439,0.00000583721,0.00002745901,0.0001073313],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03385415,"threshold_uncertainty_score":0.7598858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06038478894362557,"score_gpt":0.4112908432084104,"score_spread":0.3509060542647848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}