{"id":"W2126048792","doi":"10.1200/jco.2003.03.042","title":"Randomized, Double-Blind, Controlled Trial of Mitoxantrone/Prednisone and Clodronate Versus Mitoxantrone/Prednisone and Placebo in Patients With Hormone-Refractory Prostate Cancer and Pain","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Bone health and treatments","field":"Medicine","cited_by":248,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nova Scotia Cancer Centre","funders":"","keywords":"Medicine; Mitoxantrone; Placebo; Prednisone; Clinical endpoint; Prostate cancer; Internal medicine; Palliative care; Analgesic; Bone pain; Quality of life (healthcare); Randomized controlled trial; Oncology; Surgery; Cancer; Chemotherapy; Anesthesia; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001892326,0.00160469,0.004996839,0.0007506441,0.0007038129,0.001106169,0.00117365,0.002249214,0.008955907],"category_scores_gemma":[0.003007477,0.0009783403,0.001697208,0.000616878,0.001703001,0.001024924,0.0004503141,0.00242088,0.001299415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007351405,"about_ca_system_score_gemma":0.001527369,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00129058,"about_ca_topic_score_gemma":0.002766733,"domain_scores_codex":[0.9989032,0.0006432465,0.00009837024,0.0001607478,0.00007487276,0.0001196221],"domain_scores_gemma":[0.9983349,0.0005765033,0.0003769279,0.0000993561,0.0001141156,0.0004982115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9894463,0.003199972,0.0001762011,0.0004834862,0.0003824054,0.00001937296,0.00001851368,0.00008954071,0.0008379964,0.00004941763,0.0002135509,0.005083193],"study_design_scores_gemma":[0.9776341,0.021482,0.0003396039,0.00001605442,0.000115299,0.00001043927,0.000007239067,0.0001414769,0.00008164901,0.0000348034,0.000132785,0.000004568523],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9701026,0.008535196,0.001196908,0.001038414,0.002372455,0.01256079,0.001207971,0.0002789652,0.002706768],"genre_scores_gemma":[0.9761732,0.003408185,0.002436511,0.001440008,0.001344324,0.01126728,0.000716203,0.00002400712,0.003190332],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008955907,"threshold_uncertainty_score":0.02996045,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06038478894362557,"score_gpt":0.4112908432084104,"score_spread":0.3509060542647848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}