{"id":"W2126054845","doi":"10.1093/carcin/bgv035","title":"The effect of environmental chemicals on the tumor microenvironment","year":2015,"lang":"en","type":"review","venue":"Carcinogenesis","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":151,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"National Institute of Environmental Health Sciences; King Abdulaziz City for Science and Technology; Università degli Studi di Firenze; Ministerstvo Zdravotnictví Ceské Republiky; King Fahd University of Petroleum and Minerals; Associazione Italiana per la Ricerca sul Cancro; Agence Nationale de la Recherche; National Cancer Institute; National Institutes of Health; Fondazione Cariplo; Grantová Agentura České Republiky; Univerzita Karlova v Praze","keywords":"Tumor microenvironment; Stromal cell; Carcinogenesis; Immune system; Cancer research; Carcinogen; Extracellular matrix; Epigenetics; Biology; Angiogenesis; Epigenome; Cancer; Chemistry; Immunology; Cell biology; DNA methylation; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002701024,0.000817512,0.0008874924,0.001995275,0.0003092867,0.0009797898,0.0005998085,0.000876268,0.003410621],"category_scores_gemma":[0.0004101492,0.0001866821,0.000410978,0.001848205,0.0005121412,0.001293539,0.0006287244,0.001263916,0.00165877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006288805,"about_ca_system_score_gemma":0.0009215921,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009376282,"about_ca_topic_score_gemma":0.001344913,"domain_scores_codex":[0.9998456,0.00002628459,0.00001699973,0.0000337373,0.00006008477,0.0000172596],"domain_scores_gemma":[0.9997826,0.00009517027,0.00002887199,0.000008748774,0.00006651316,0.00001813226],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006447238,0.00006363678,0.0003851028,0.01965271,0.00008808231,0.0003639733,0.000111447,0.0005819567,0.00694333,0.007742773,0.03252978,0.9314728],"study_design_scores_gemma":[0.000003500759,0.00004870738,0.0006835791,0.001477704,0.00005299368,0.001051805,0.00006452833,0.00005466717,0.001193309,0.002298419,0.9930586,0.00001234361],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002127584,0.9968033,0.0002777167,0.0003539829,0.0002863264,0.000004558909,0.00003087802,0.00001520728,0.002015319],"genre_scores_gemma":[0.001049829,0.9976048,0.0001612898,0.0001422914,0.0001388804,0.000004817156,0.00002809719,0.000001807212,0.0008680091],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003410621,"threshold_uncertainty_score":0.01140964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02342975889761428,"score_gpt":0.2732641785637279,"score_spread":0.2498344196661136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}