{"id":"W2126080585","doi":"10.1515/bc.2006.094","title":"Human kallikrein 4: enzymatic activity, inhibition, and degradation of extracellular matrix proteins","year":2006,"lang":"en","type":"article","venue":"Biological Chemistry","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Kallikrein; Proteases; Extracellular matrix; Biochemistry; Pichia pastoris; Enzyme; Chemistry; Extracellular; Protease; Serine; Serine protease; Recombinant DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003788832,0.0003872706,0.0002766243,0.0001956551,0.00011921,0.000255301,0.0002139853,0.0002044147,0.0006416741],"category_scores_gemma":[0.0004044074,0.0001415831,0.0002026474,0.0001485722,0.0001974236,0.0002585694,0.0001277733,0.000232644,0.0002128971],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003371954,"about_ca_system_score_gemma":0.000287842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009464059,"about_ca_topic_score_gemma":0.000648541,"domain_scores_codex":[0.9997631,0.00006806343,0.00002633591,0.00003319166,0.00005718271,0.00005217391],"domain_scores_gemma":[0.9998976,0.00002850251,0.00003314813,0.00001056343,0.0000131132,0.00001704714],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004120691,0.00004308644,0.0008373025,0.00007896956,0.00001976039,0.00005588065,0.000008909444,0.0001762085,0.9941807,0.00005056356,0.00005152687,0.004084937],"study_design_scores_gemma":[0.00001413914,0.0002343433,0.006018658,0.000003094054,0.00002052656,0.0002729525,0.000004925572,0.0004828206,0.9915475,0.00002211996,0.00137525,0.000003522068],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855524,0.009744743,0.003376553,0.00009961316,0.00002009291,0.00002581231,0.0002597689,0.00003903527,0.0008820294],"genre_scores_gemma":[0.9903976,0.00254676,0.003941156,0.00004275935,0.00001362743,0.00002741629,0.0005792463,0.0000157051,0.00243584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009464059,"threshold_uncertainty_score":0.002446532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02375607233306859,"score_gpt":0.2679700615428224,"score_spread":0.2442139892097538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}