{"id":"W2126080585","doi":"10.1515/bc.2006.094","title":"Human kallikrein 4: enzymatic activity, inhibition, and degradation of extracellular matrix proteins","year":2006,"lang":"en","type":"article","venue":"Biological Chemistry","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Kallikrein; Proteases; Extracellular matrix; Biochemistry; Pichia pastoris; Enzyme; Chemistry; Extracellular; Protease; Serine; Serine protease; Recombinant DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000122699,0.0001308661,0.0002414446,0.00001909603,0.00006730721,0.00001128749,0.00003497066,0.000188001,0.0002341596],"category_scores_gemma":[0.0000587384,0.0001023838,0.00007054978,0.00008771737,0.000146885,0.00004098277,0.00003126588,0.00009204448,0.000003343466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002551786,"about_ca_system_score_gemma":0.00002264504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006825067,"about_ca_topic_score_gemma":0.000002341787,"domain_scores_codex":[0.9992093,0.00001872713,0.0002730092,0.0002215266,0.000130995,0.0001464477],"domain_scores_gemma":[0.9995649,0.00003344594,0.0001409096,0.0001430528,0.00005437267,0.00006334321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002710916,0.0001965554,0.0238734,0.0002090319,0.000009707399,0.000007993121,0.000008533147,0.000001270082,0.974335,0.0006789769,0.000123718,0.0005286686],"study_design_scores_gemma":[0.0007019845,0.0001063893,0.1225845,0.00009902326,0.00003194185,0.00003717491,0.00001645082,0.000079483,0.8739651,0.001879204,0.0003677217,0.0001310368],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967266,0.001616819,0.0002983123,0.000206219,0.000009069528,0.0002363925,0.000009265421,0.00006318687,0.0008341032],"genre_scores_gemma":[0.9956271,0.00001612511,0.0006998538,0.00001106344,0.0001475849,0.00001884448,0.0001499212,0.000008304172,0.003321199],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1003699,"threshold_uncertainty_score":0.417509,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02375607233306859,"score_gpt":0.2679700615428224,"score_spread":0.2442139892097538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}