{"id":"W2126123579","doi":"10.1093/emboj/19.4.581","title":"Crystal structure of a class I α1,2‐mannosidase involved in N‐glycan processing and endoplasmic reticulum quality control","year":2000,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":103,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; McGill University; McGill University Health Centre; Hospital for Sick Children","funders":"National Institute of General Medical Sciences; Medical Research Council; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Medical Research Council Canada; U.S. Department of Energy","keywords":"Endoplasmic reticulum; Biology; Mannosidase; Glycan; STIM1; Crystal (programming language); Cell biology; Biochemistry; Enzyme; Glycoprotein; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001684549,0.0003456394,0.0003745267,0.0001438651,0.0004473178,0.0008320156,0.0005158008,0.0005748604,0.0009152221],"category_scores_gemma":[0.0003000752,0.0001458711,0.0001742688,0.0003346022,0.0002426491,0.0002588417,0.00014631,0.001299738,0.0002238176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001274338,"about_ca_system_score_gemma":0.0009723702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007239909,"about_ca_topic_score_gemma":0.006169024,"domain_scores_codex":[0.9999371,0.00000664477,0.000003742281,0.00001583963,0.00002288574,0.00001390547],"domain_scores_gemma":[0.9998685,0.00002128914,0.00002790321,0.000005588941,0.00002401062,0.00005270484],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003453321,0.0008970282,0.01005985,0.0004637904,0.0001920786,0.00440111,0.0006264435,0.009862132,0.9167148,0.007338765,0.02307763,0.02291309],"study_design_scores_gemma":[0.001449456,0.001809854,0.1190239,0.0001723486,0.0003978998,0.00951962,0.002163192,0.106504,0.641287,0.004138805,0.1133055,0.0002284412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9835929,0.004248095,0.00222033,0.001582907,0.0003350186,0.00003506198,0.002493524,0.0001740741,0.005318167],"genre_scores_gemma":[0.9769049,0.002813354,0.005014518,0.0004016712,0.00006411703,0.00003234444,0.007646362,0.00004153397,0.00708116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007239909,"threshold_uncertainty_score":0.01439553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01085603491824156,"score_gpt":0.2374181639230806,"score_spread":0.2265621290048391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}