{"id":"W2126167719","doi":"10.1021/bi050607y","title":"Purification and Biochemical Characterization of a Pyruvate-Specific Class II Aldolase, HpaI","year":2005,"lang":"en","type":"article","venue":"Biochemistry","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"University of Guelph","keywords":"Aldolase A; Chemistry; Pyruvate decarboxylase; Enzyme; Active site; Stereochemistry; Aldolase B; Biochemistry; Fructose-bisphosphate aldolase; Enzyme kinetics; Oxalate; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002221714,0.0006221422,0.0004754717,0.0002922277,0.0001548293,0.000622844,0.0002711091,0.0002393233,0.0005089144],"category_scores_gemma":[0.0004278902,0.0001397429,0.0003274422,0.0005999337,0.0001745206,0.0003927491,0.0002645287,0.0007906805,0.0006874472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002983516,"about_ca_system_score_gemma":0.0002446813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001290548,"about_ca_topic_score_gemma":0.0006750433,"domain_scores_codex":[0.9998154,0.00002082358,0.0000204276,0.00004830624,0.00006822772,0.0000269811],"domain_scores_gemma":[0.9997891,0.00002389327,0.00003218955,0.00002243987,0.00007187795,0.0000605582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003285913,0.000026935,0.0003942485,0.0000533099,0.000006638724,0.00004345123,0.00001333765,0.00006361209,0.9968535,0.00006762237,0.00009953676,0.002344931],"study_design_scores_gemma":[0.00001413292,0.0001681021,0.01418357,0.00001620706,0.00003754802,0.0008494749,0.00006186066,0.002050359,0.9622779,0.0001075474,0.02021848,0.00001486957],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9077787,0.01338234,0.06353634,0.0007861527,0.0003254395,0.0004203055,0.008842528,0.0005570406,0.004371205],"genre_scores_gemma":[0.8766679,0.008839173,0.0548703,0.0002968649,0.0001736352,0.0001924206,0.04431516,0.0002045269,0.01443999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001290548,"threshold_uncertainty_score":0.002566099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006364143452886494,"score_gpt":0.2081581580851488,"score_spread":0.2017940146322623,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}