{"id":"W2126178560","doi":"10.1002/cbic.200700014","title":"Simple and Rapid Colorimetric Biosensors Based on DNA Aptamer and Noncrosslinking Gold Nanoparticle Aggregation","year":2007,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":223,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Aptamer; Colloidal gold; Nanoparticle; Biosensor; Chemistry; DNA; Nanotechnology; Colorimetry; Salt (chemistry); Biophysics; Chromatography; Materials science; Biochemistry; Biology; Molecular biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003651226,0.0001827345,0.0001587782,0.000109655,0.0001042095,0.00003853564,0.00006575607,0.0001827057,0.000001542152],"category_scores_gemma":[0.000162671,0.0001679645,0.00005630215,0.000290068,0.0001782081,0.000004883337,0.00005792155,0.00008220308,0.000001521076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000193722,"about_ca_system_score_gemma":0.00001631642,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000062724,"about_ca_topic_score_gemma":0.000006555277,"domain_scores_codex":[0.9989323,0.00001984325,0.0002038878,0.000436346,0.0001303579,0.0002772502],"domain_scores_gemma":[0.9994034,0.00004225062,0.0001004228,0.0002644008,0.00007769925,0.0001118885],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001040754,0.00004516406,0.001937382,0.00001261001,0.00001758466,0.00000350283,0.00001103858,0.000001375905,0.9800319,0.00001336089,0.0002369857,0.01758501],"study_design_scores_gemma":[0.0004776025,0.0002822034,0.002095562,0.00001676573,0.00002647578,0.000007532326,0.00004513546,0.000413862,0.9926788,0.00003246476,0.003698846,0.0002247471],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981765,0.000360445,0.0005959066,0.00008845407,0.0000267705,0.0001229014,0.00000644899,0.00004916338,0.0005733967],"genre_scores_gemma":[0.9966723,0.00008400888,0.002368519,0.0005256904,0.0001146979,0.00000306658,0.00006016798,0.00002103348,0.000150459],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01736026,"threshold_uncertainty_score":0.6849392,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00929159551183106,"score_gpt":0.2606234861216513,"score_spread":0.2513318906098203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}