{"id":"W2126178560","doi":"10.1002/cbic.200700014","title":"Simple and Rapid Colorimetric Biosensors Based on DNA Aptamer and Noncrosslinking Gold Nanoparticle Aggregation","year":2007,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":223,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Aptamer; Colloidal gold; Nanoparticle; Biosensor; Chemistry; DNA; Nanotechnology; Colorimetry; Salt (chemistry); Biophysics; Chromatography; Materials science; Biochemistry; Biology; Molecular biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001238879,0.001646826,0.0008238186,0.001144262,0.000414781,0.0009356278,0.001957095,0.001751526,0.001762024],"category_scores_gemma":[0.001677355,0.001532852,0.0006033157,0.0006299282,0.0008460089,0.001178089,0.001526312,0.002267953,0.002063703],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001003306,"about_ca_system_score_gemma":0.0006379277,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004587605,"about_ca_topic_score_gemma":0.001280739,"domain_scores_codex":[0.9975879,0.0002426265,0.0001230513,0.0003935694,0.00148507,0.0001677019],"domain_scores_gemma":[0.9992542,0.0002130246,0.0001436519,0.00007513515,0.000153495,0.0001604419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005732141,0.0000586152,0.00011019,0.00017694,0.00001649989,0.00008265595,0.00004220566,0.0001731936,0.9867297,0.0007145255,0.0005445183,0.01129359],"study_design_scores_gemma":[0.00001375074,0.00009083456,0.0002631056,0.00000803552,0.000006519905,0.0002470237,0.00001043472,0.00139535,0.9938262,0.0002443295,0.003870695,0.00002378023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2221686,0.01907719,0.729107,0.001910624,0.002537268,0.00202603,0.001272193,0.008496122,0.01340506],"genre_scores_gemma":[0.3867687,0.007599485,0.5710766,0.001068955,0.0002968743,0.001291726,0.001153722,0.0003361887,0.03040775],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001957095,"threshold_uncertainty_score":0.007279575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00929159551183106,"score_gpt":0.2606234861216513,"score_spread":0.2513318906098203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}