{"id":"W2126232325","doi":"10.1016/s0928-4680(02)00008-1","title":"Early and persistent activation of myocardial apoptosis, bax and caspases: insights into mechanisms of progression of heart failure","year":2002,"lang":"en","type":"article","venue":"Pathophysiology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Toronto; St. Michael's Hospital","funders":"","keywords":"Apoptosis; Caspase; Heart failure; Cell biology; Medicine; Internal medicine; Cancer research; Biology; Programmed cell death; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004563152,0.00009376383,0.0002092435,0.00004948236,0.00003346119,0.000001909996,0.00003716542,0.0001659122,0.00000572643],"category_scores_gemma":[0.00001834651,0.00007714189,0.00007061257,0.00004914697,0.00010251,0.000005132536,0.00006851492,0.00003367741,2.045602e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003316326,"about_ca_system_score_gemma":0.000007906259,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002657771,"about_ca_topic_score_gemma":0.00000184329,"domain_scores_codex":[0.9993909,0.00006352516,0.0001846352,0.0002044573,0.00007409079,0.00008237184],"domain_scores_gemma":[0.9995986,0.00001097941,0.0001430899,0.0001349813,0.00007880082,0.00003352705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006107156,0.00005875777,0.000082185,0.00007618815,0.00003022706,9.539667e-8,0.0002720986,0.00001605485,0.9959654,0.0004781972,0.00002396412,0.002935747],"study_design_scores_gemma":[0.0003983332,0.001677253,0.002986857,0.00003774466,0.00002727848,0.000002030052,0.0001255653,0.0002584913,0.992572,0.001678965,0.0001531267,0.00008231889],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982654,0.0007391095,0.0007077025,0.0000553282,0.00004902427,0.0001609962,0.000004091168,0.000002536026,0.00001583249],"genre_scores_gemma":[0.9970704,0.0003634626,0.002450663,0.0000198676,0.00003854956,0.000008820268,0.00002869835,0.000008090487,0.0000114184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003393377,"threshold_uncertainty_score":0.3145755,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006234958313904777,"score_gpt":0.2101533428257853,"score_spread":0.2039183845118806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}