{"id":"W2126257962","doi":"10.1084/jem.2129insight4","title":"Inborn errors underlying herpes simplex encephalitis: From TLR3 to IRF3","year":2015,"lang":"en","type":"letter","venue":"The Journal of Experimental Medicine","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"National Institute of Allergy and Infectious Diseases; Agence Nationale de la Recherche","keywords":"Encephalitis; Herpes simplex virus; Virology; HSL and HSV; Medicine; Virus; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003907648,0.0007197428,0.00040804,0.0002797654,0.0003526387,0.0006822707,0.000374807,0.001103792,0.006040827],"category_scores_gemma":[0.0003230621,0.0002363205,0.0005313197,0.0001119841,0.0007166752,0.0003595763,0.0005660227,0.001935674,0.001085563],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003561589,"about_ca_system_score_gemma":0.0003516263,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002549184,"about_ca_topic_score_gemma":0.0002732419,"domain_scores_codex":[0.9998181,0.00004775451,0.0000188805,0.00003635828,0.00002782483,0.0000511172],"domain_scores_gemma":[0.9998795,0.00001702182,0.00003801663,0.00002185053,0.00001250737,0.0000310542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.008987438,0.0007596897,0.01853582,0.001229553,0.0003873089,0.02777043,0.0004915663,0.0004214077,0.7435208,0.01345772,0.02263949,0.1617988],"study_design_scores_gemma":[0.001561492,0.005163162,0.1164275,0.001566024,0.001436482,0.1546918,0.002623532,0.00343927,0.3441257,0.02372755,0.3450361,0.0002012226],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.7997143,0.1186673,0.01180574,0.03108944,0.007848917,0.00018704,0.0009472903,0.0007360462,0.02900394],"genre_scores_gemma":[0.9404469,0.03458174,0.002993797,0.004862995,0.001762014,0.00009249344,0.0005310013,0.00008158565,0.01464752],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.006040827,"threshold_uncertainty_score":0.02020866,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08085624395602642,"score_gpt":0.3505287847152803,"score_spread":0.2696725407592539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}