{"id":"W2126257962","doi":"10.1084/jem.2129insight4","title":"Inborn errors underlying herpes simplex encephalitis: From TLR3 to IRF3","year":2015,"lang":"en","type":"letter","venue":"The Journal of Experimental Medicine","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"National Institute of Allergy and Infectious Diseases; Agence Nationale de la Recherche","keywords":"Encephalitis; Herpes simplex virus; Virology; HSL and HSV; Medicine; Virus; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008663805,0.0004215887,0.000939306,0.0002786783,0.0001508705,0.00001433419,0.0009785461,0.0005291644,0.003861052],"category_scores_gemma":[0.000269139,0.0002406701,0.0001643174,0.0001310415,0.0005584368,0.00009896817,0.0001950589,0.001665435,0.0003765472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002620652,"about_ca_system_score_gemma":0.0001746912,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000768375,"about_ca_topic_score_gemma":0.000008187379,"domain_scores_codex":[0.9970362,0.001115531,0.0009317219,0.0002062162,0.0002400794,0.0004702976],"domain_scores_gemma":[0.9979804,0.0006904197,0.0006385228,0.0004322779,0.0001943044,0.00006413267],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009874181,0.00003978474,0.000001723956,0.000005618939,0.0004053726,0.000125211,0.006126239,4.998118e-7,0.2702804,0.000005032105,0.7204571,0.001565559],"study_design_scores_gemma":[0.001880134,0.002473683,0.00004611883,0.0007609185,0.0001913928,0.0008078467,0.01536447,2.249472e-7,0.1185067,0.0001107284,0.8596222,0.0002355589],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.2771779,0.1232225,0.0001028129,0.5868638,0.009641463,0.0005088788,0.00007702366,0.00004415153,0.002361509],"genre_scores_gemma":[0.597643,0.0003050145,0.00005880506,0.3902725,0.002707832,0.00001019722,0.0001526252,0.0000818884,0.008768093],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.3204651,"threshold_uncertainty_score":0.9970496,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08085624395602642,"score_gpt":0.3505287847152803,"score_spread":0.2696725407592539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}