{"id":"W2126269101","doi":"10.1093/ndt/gfp031","title":"Fabry disease: progression of nephropathy, and prevalence of cardiac and cerebrovascular events before enzyme replacement therapy","year":2009,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":366,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Center for Research Resources; National Institute of Neurological Disorders and Stroke; University of California, San Francisco; National Institutes of Health; Cedars-Sinai Medical Center","keywords":"Medicine; Fabry disease; Enzyme replacement therapy; Internal medicine; Proteinuria; Renal function; Nephropathy; Cardiology; Stroke (engine); Renal replacement therapy; Kidney disease; Disease; Diabetes mellitus; Endocrinology; Kidney","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008567994,0.0001304888,0.0002665132,0.0008429651,0.0002870103,0.0004542521,0.0001895428,0.0003492508,0.0009532869],"category_scores_gemma":[0.00249531,0.0001262301,0.0001920842,0.0007498947,0.0002099495,0.0003656282,0.000185502,0.0003105522,0.000108448],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003618432,"about_ca_system_score_gemma":0.0003501986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005449924,"about_ca_topic_score_gemma":0.005800142,"domain_scores_codex":[0.9996181,0.00007765101,0.00004763108,0.00009317338,0.0001072551,0.00005622261],"domain_scores_gemma":[0.9975782,0.0003849431,0.001489971,0.0000633444,0.0002229313,0.0002606194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00005109537,0.000005825163,0.9993501,0.000003501676,0.00001066857,0.00005828662,0.00002124572,0.00001431704,0.00007188739,0.000003720745,0.00001871048,0.0003906141],"study_design_scores_gemma":[0.000002109737,0.00004184605,0.9992636,0.00000265423,0.000008636955,0.0005199952,0.0000268702,0.00004627186,0.00004009631,0.000004505594,0.00004221096,0.000001201534],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999199,0.0002773766,0.00005169872,0.0000133483,9.166059e-7,0.000006231083,0.0002650098,0.000002380362,0.00018407],"genre_scores_gemma":[0.9995303,0.00008478648,0.00005770703,0.00000643225,0.000003605719,0.000003156822,0.000274082,5.866175e-7,0.00003926419],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005449924,"threshold_uncertainty_score":0.01083642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01002345083674984,"score_gpt":0.2838305462858449,"score_spread":0.273807095449095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}