{"id":"W2126275728","doi":"10.1038/cmi.2014.50","title":"The activating effect of IFN-γ on monocytes/macrophages is regulated by the LIF–trophoblast–IL-10 axis via Stat1 inhibition and Stat3 activation","year":2014,"lang":"en","type":"article","venue":"Cellular and Molecular Immunology","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":70,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre intégré universitaire de santé et de services sociaux de la Mauricie-et-du-Centre-du-Québec; Université du Québec à Trois-Rivières; Institut National de la Recherche Scientifique; Innovation and Economic Development Trois Rivières; Université du Québec à Montréal","funders":"","keywords":"Trophoblast; Leukemia inhibitory factor; CD14; Tumor necrosis factor alpha; Macrophage; Cell biology; Cytotoxic T cell; CD40; Biology; Monocyte; Chemistry; Cytokine; Immunology; Interleukin 6; Immune system; Placenta; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002862345,0.0004508097,0.0002284555,0.0003505637,0.0002322732,0.0004289715,0.0001712816,0.0002781768,0.002860642],"category_scores_gemma":[0.0001719299,0.0002008735,0.0004677516,0.0001337272,0.0003869233,0.0001949914,0.0003464564,0.001183832,0.0005861399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003542904,"about_ca_system_score_gemma":0.0006344051,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008148608,"about_ca_topic_score_gemma":0.001411615,"domain_scores_codex":[0.9996684,0.0000733511,0.00002667652,0.00002888334,0.00005089398,0.0001518885],"domain_scores_gemma":[0.9998617,0.00002594758,0.00003916261,0.00001974542,0.00001392954,0.00003935197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001405992,0.00005659967,0.0008541883,0.00008818274,0.00001048678,0.0001377044,0.00004359733,0.00007276058,0.9933317,0.0003137335,0.0001509113,0.003534106],"study_design_scores_gemma":[0.0001351144,0.0004774217,0.01752754,0.00003985265,0.00004214666,0.0003788857,0.000191685,0.0006789676,0.975462,0.0003263154,0.004730837,0.000009312586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856903,0.004707373,0.003169767,0.0006105007,0.0001728964,0.00004823812,0.0009252256,0.000106916,0.004568725],"genre_scores_gemma":[0.9934783,0.001602173,0.001443969,0.0001789742,0.00003476551,0.00005263567,0.0005112678,0.00001850213,0.002679437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002860642,"threshold_uncertainty_score":0.009569764,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003162046881005636,"score_gpt":0.1970992204439838,"score_spread":0.1939371735629781,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}