{"id":"W2126275728","doi":"10.1038/cmi.2014.50","title":"The activating effect of IFN-γ on monocytes/macrophages is regulated by the LIF–trophoblast–IL-10 axis via Stat1 inhibition and Stat3 activation","year":2014,"lang":"en","type":"article","venue":"Cellular and Molecular Immunology","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":70,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre intégré universitaire de santé et de services sociaux de la Mauricie-et-du-Centre-du-Québec; Université du Québec à Trois-Rivières; Institut National de la Recherche Scientifique; Innovation and Economic Development Trois Rivières; Université du Québec à Montréal","funders":"","keywords":"Trophoblast; Leukemia inhibitory factor; CD14; Tumor necrosis factor alpha; Macrophage; Cell biology; Cytotoxic T cell; CD40; Biology; Monocyte; Chemistry; Cytokine; Immunology; Interleukin 6; Immune system; Placenta; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000661137,0.0002838534,0.0003764631,0.00007210772,0.0005156401,0.00003088641,0.0001545907,0.0002807019,0.00003939601],"category_scores_gemma":[0.0002294296,0.0001733822,0.00008585098,0.0001363604,0.0006490341,0.00007193208,0.0001226431,0.0003424752,0.00002112116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002958821,"about_ca_system_score_gemma":0.00002187525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001086672,"about_ca_topic_score_gemma":0.000001115212,"domain_scores_codex":[0.9973974,0.001349013,0.0003580506,0.0004837167,0.00006216947,0.0003497161],"domain_scores_gemma":[0.9984015,0.0005976604,0.000309237,0.000575473,0.00009725294,0.00001885927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004418726,0.00002838158,0.00006637484,0.000039333,0.0002803153,0.000001638705,0.000520767,0.000003310073,0.956041,0.0002578001,0.0004434219,0.04187574],"study_design_scores_gemma":[0.0013614,0.001510052,0.00085501,0.00008291983,0.00004678658,0.0000382212,0.0001244665,0.00001451103,0.9850037,0.0003835778,0.01041335,0.0001660028],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9732396,0.0222357,0.002883082,0.0004785815,0.00023302,0.000567927,0.00001709724,0.00003339849,0.0003115899],"genre_scores_gemma":[0.9984859,0.0002666948,0.00001063205,0.0000848031,0.00001795526,0.00005084899,0.00008502712,0.00002883898,0.0009693045],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04170974,"threshold_uncertainty_score":0.7070321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003162046881005636,"score_gpt":0.1970992204439838,"score_spread":0.1939371735629781,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}