{"id":"W2126279424","doi":"10.1128/iai.01504-14","title":"Phosphoethanolamine Decoration of Neisseria gonorrhoeae Lipid A Plays a Dual Immunostimulatory and Protective Role during Experimental Genital Tract Infection","year":2014,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Vector Institute; National Institute of Allergy and Infectious Diseases; U.S. Department of Veterans Affairs","keywords":"Biology; Microbiology; Lipid A; Neisseria gonorrhoeae; TLR2; TLR4; Proinflammatory cytokine; Innate immune system; Cathelicidin; Antimicrobial peptides; Inflammation; Immunology; Lipopolysaccharide; Immune system; Antimicrobial","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005408423,0.0002278385,0.0002901643,0.0003055864,0.0005845811,0.0000425174,0.00004518033,0.0002498504,0.0001904454],"category_scores_gemma":[0.0004453969,0.0002300588,0.00007570962,0.0002510831,0.0003349305,0.0005616296,0.0001163114,0.0006010199,0.00003849034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001142076,"about_ca_system_score_gemma":0.00004779817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004075204,"about_ca_topic_score_gemma":0.00007298325,"domain_scores_codex":[0.9984809,0.0005339013,0.0003458918,0.0003514753,0.00003330323,0.0002545991],"domain_scores_gemma":[0.9991304,0.0001252805,0.0001923848,0.000307825,0.00020887,0.00003524904],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003324925,0.0005764933,0.06772624,0.00004309024,0.0001100821,1.431861e-7,0.0009589228,0.00003969516,0.925787,0.00008045619,0.000004603115,0.004340792],"study_design_scores_gemma":[0.001064489,0.0006945205,0.5257802,0.00001925946,0.00001785499,0.0002194074,0.0001599611,0.00005010515,0.4715084,0.00004177517,0.0003113486,0.000132639],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970782,0.0009022242,0.0002605843,0.00001720375,0.0004117828,0.0006149241,0.000008134993,0.000104836,0.0006020665],"genre_scores_gemma":[0.9994991,0.0001418583,0.00001314646,0.000005308989,0.00006172054,0.0001093051,0.00003820666,0.00002257121,0.0001087808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.458054,"threshold_uncertainty_score":0.9381526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01064598166602327,"score_gpt":0.2643679944926059,"score_spread":0.2537220128265826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}