{"id":"W2126290991","doi":"10.1128/iai.00285-07","title":"Fate of a <i>Burkholderia pseudomallei</i> Lipopolysaccharide Mutant in the Mouse Macrophage Cell Line RAW 264.7: Possible Role for the O-Antigenic Polysaccharide Moiety of Lipopolysaccharide in Internalization and Intracellular Survival","year":2007,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Burkholderia infections and melioidosis","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Burkholderia pseudomallei; Biology; Microbiology; Lipopolysaccharide; Intracellular; Melioidosis; Macrophage; Intracellular parasite; Interferon; Cell biology; Virology; Bacteria; Biochemistry; Immunology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002464479,0.0002476882,0.0004790366,0.0003905397,0.0001893014,0.00004610951,0.0001458316,0.0001933238,0.00004011239],"category_scores_gemma":[0.0002201534,0.0001727632,0.000155475,0.0005057618,0.0002164387,0.0001931752,0.00009633717,0.0005057578,8.243341e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005501192,"about_ca_system_score_gemma":0.00006845142,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01970093,"about_ca_topic_score_gemma":0.003172955,"domain_scores_codex":[0.9981443,0.0001837227,0.0008562456,0.0002615822,0.0002230692,0.0003310424],"domain_scores_gemma":[0.9985437,0.0003963451,0.0003502128,0.0004504954,0.0001795419,0.00007968039],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005968187,0.0006040733,0.06410747,0.0002126804,0.00006788995,0.000004213521,0.002027809,0.00008814877,0.9278719,0.0004416319,0.000008934254,0.003968362],"study_design_scores_gemma":[0.003322545,0.0005649326,0.07066082,0.0001296669,0.0001663528,0.00008512216,0.002149206,0.002948744,0.9194244,0.0001544148,0.0002155336,0.0001782323],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985926,0.001164733,0.01122666,0.0001829554,0.000287586,0.001055028,0.00001709459,0.00002802903,0.0001119142],"genre_scores_gemma":[0.9966958,0.002742929,0.0001385841,0.0001438386,0.00008738624,0.00005161702,0.00001271906,0.00002946881,0.0000976942],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01652798,"threshold_uncertainty_score":0.986827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01730528167185592,"score_gpt":0.2717873073740922,"score_spread":0.2544820257022363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}