{"id":"W2126290991","doi":"10.1128/iai.00285-07","title":"Fate of a <i>Burkholderia pseudomallei</i> Lipopolysaccharide Mutant in the Mouse Macrophage Cell Line RAW 264.7: Possible Role for the O-Antigenic Polysaccharide Moiety of Lipopolysaccharide in Internalization and Intracellular Survival","year":2007,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Burkholderia infections and melioidosis","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Burkholderia pseudomallei; Biology; Microbiology; Lipopolysaccharide; Intracellular; Melioidosis; Macrophage; Intracellular parasite; Interferon; Cell biology; Virology; Bacteria; Biochemistry; Immunology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001401222,0.0002568169,0.0002510214,0.0001275233,0.0001550836,0.0002904963,0.0001934346,0.0003991787,0.0005460068],"category_scores_gemma":[0.00009780247,0.0001293665,0.0002246829,0.0001057631,0.0001763965,0.0002093199,0.0001861541,0.0005381939,0.0004261384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002020948,"about_ca_system_score_gemma":0.000133579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007315379,"about_ca_topic_score_gemma":0.0004355918,"domain_scores_codex":[0.9998128,0.00003697984,0.00002266326,0.00003185558,0.00004557639,0.00005028304],"domain_scores_gemma":[0.9998659,0.00002128995,0.00004161177,0.00002007677,0.00002047411,0.00003063129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000683671,0.00001545785,0.0002163895,0.000008671393,0.000001133001,0.00003390729,0.00001166476,0.00001888729,0.9994111,0.00003961303,0.000007713218,0.0001670278],"study_design_scores_gemma":[0.00001342724,0.0003962565,0.008184329,0.000005045997,0.000007380451,0.0003505261,0.00009198256,0.001165788,0.9891375,0.00005202747,0.0005876319,0.000008052192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982657,0.0003003246,0.0007921637,0.00005892233,0.00001142638,0.000008874587,0.0002146995,0.00001833392,0.0003296638],"genre_scores_gemma":[0.9972588,0.0001885302,0.0009959656,0.00003432476,0.000004960751,0.00002346228,0.0004524526,0.00001045817,0.001031003],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007315379,"threshold_uncertainty_score":0.001826584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01730528167185592,"score_gpt":0.2717873073740922,"score_spread":0.2544820257022363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}