{"id":"W2126364275","doi":"10.1016/j.placenta.2011.06.003","title":"Stimulation of serotonergic 5-HT2A receptor signaling increases placental aromatase (CYP19) activity and expression in BeWo and JEG-3 human choriocarcinoma cells","year":2011,"lang":"en","type":"article","venue":"Placenta","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research","keywords":"Serotonergic; Stimulation; Aromatase; Endocrinology; Internal medicine; Chemistry; Receptor; 5-HT receptor; Cell biology; Serotonin; Biology; Medicine; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001321127,0.0001474698,0.0001572304,0.00005715785,0.00006470571,0.000009625929,0.00006404369,0.0001699659,0.00002279594],"category_scores_gemma":[0.00001618889,0.0001364895,0.00003022125,0.00004944067,0.00007479294,0.00001329157,0.000114296,0.0001047621,0.000001710541],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001274233,"about_ca_system_score_gemma":0.00001521562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002410961,"about_ca_topic_score_gemma":0.00001635107,"domain_scores_codex":[0.9992035,0.0001065869,0.0001583896,0.0002856077,0.00008475182,0.0001611754],"domain_scores_gemma":[0.9996165,0.00002212149,0.00009815181,0.000155031,0.00001422363,0.00009396936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005348493,0.0001894157,0.05650642,0.00004707801,0.00001699122,0.00000469126,0.000169034,0.00001500527,0.9422336,0.0000052631,0.00007588411,0.0002017807],"study_design_scores_gemma":[0.001324834,0.0003353324,0.02828731,0.00007614479,0.00001849056,0.000007768281,0.0001081951,0.000163961,0.9694985,0.00001223844,0.00002232679,0.0001448828],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987199,0.0007825515,0.00001454565,0.000003026057,0.00003919777,0.0002977707,0.00003864139,0.000008250246,0.00009609994],"genre_scores_gemma":[0.9992855,0.0001303523,0.0003556361,0.000008124529,0.00003206263,0.00001131541,0.0001366676,0.00001544988,0.00002492087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02821911,"threshold_uncertainty_score":0.5565881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01303555145903168,"score_gpt":0.2327816526924817,"score_spread":0.21974610123345,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}