{"id":"W2126403521","doi":"10.1128/iai.00466-12","title":"Leptospira interrogans Catalase Is Required for Resistance to H <sub>2</sub> O <sub>2</sub> and for Virulence","year":2012,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Leptospirosis research and findings","field":"Immunology and Microbiology","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Conseil Régional, Île-de-France","keywords":"Leptospira interrogans; Catalase; Leptospira; Microbiology; Biology; Virulence; Bacteria; Innate immune system; Pathogenic bacteria; Reactive oxygen species; Oxidative stress; Immune system; Serotype; Immunology; Biochemistry; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006995343,0.0002455186,0.0003035325,0.0001879215,0.0008122658,0.0000679708,0.000134914,0.0002888886,0.00002035667],"category_scores_gemma":[0.0005377345,0.0002383956,0.0001159247,0.0001955202,0.0003032165,0.0005086461,0.0001734279,0.0003513013,0.0001066168],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008885594,"about_ca_system_score_gemma":0.00004330535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001183278,"about_ca_topic_score_gemma":0.0002621661,"domain_scores_codex":[0.9984832,0.0001368044,0.0003134372,0.0003341346,0.00004834698,0.0006840239],"domain_scores_gemma":[0.9989763,0.0002708446,0.0001198497,0.0003173501,0.000174178,0.0001414293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005986833,0.000169742,0.006319338,0.0001145927,0.00008565565,1.864252e-7,0.001457797,1.227165e-7,0.9656151,0.0002920507,0.005985634,0.01936111],"study_design_scores_gemma":[0.001542533,0.0005551563,0.02855816,0.00006792769,0.00003520804,0.00001700619,0.0001715311,0.000002937854,0.8963087,0.0001664397,0.07231151,0.0002628778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934072,0.001131509,0.003086607,0.0003957665,0.0005504458,0.0009479958,0.0002424938,0.00008171044,0.0001562688],"genre_scores_gemma":[0.9979016,0.0006024902,0.00006884193,0.0006085863,0.00007497959,0.0003231455,0.0001289595,0.00002842537,0.0002629239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06930638,"threshold_uncertainty_score":0.9721489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02711553337148572,"score_gpt":0.285440647481139,"score_spread":0.2583251141096533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}