{"id":"W2126541892","doi":"10.1016/s0024-3205(01)01012-8","title":"Biochemical and biophysical demonstration of GPCR oligomerization in mammalian cells","year":2001,"lang":"en","type":"article","venue":"Life Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"G protein-coupled receptor; Receptor; HEK 293 cells; Cell biology; Agonist; Chemistry; Biology; Biophysics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001205585,0.00004478398,0.00005843732,0.00003222623,0.0000305658,0.000009626358,0.0000646979,0.00004821448,0.00001451977],"category_scores_gemma":[0.00001798109,0.00003879161,0.00001530853,0.0001491954,0.0001292118,0.000005009415,0.00001590291,0.00001932503,8.130319e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001438661,"about_ca_system_score_gemma":0.00002865533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002321171,"about_ca_topic_score_gemma":0.00000461913,"domain_scores_codex":[0.9995505,0.00001751394,0.0001067386,0.0001562217,0.00008039737,0.00008865345],"domain_scores_gemma":[0.9998643,0.00000477306,0.0000356272,0.00004570777,0.00001350952,0.00003602077],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000006490255,0.00001507659,0.003239012,0.000003189979,9.700425e-7,2.148801e-7,0.00001969703,0.00004832914,0.9957539,0.0003891904,0.00002135702,0.0005026035],"study_design_scores_gemma":[0.00008725441,0.0001067277,0.001393524,0.000006242492,0.000001514174,0.000001533097,0.00009702176,0.0006150188,0.9973169,0.0001136679,0.0002094987,0.00005107097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977004,0.0001776599,0.001589321,0.00007908051,0.00004932617,0.00004097485,0.000001312007,0.000001991901,0.0003599568],"genre_scores_gemma":[0.998546,0.0001501606,0.0011696,0.00004787462,0.00005625011,0.000001734967,0.000005549717,0.000002006117,0.00002082534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001845488,"threshold_uncertainty_score":0.1581876,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01192824701803726,"score_gpt":0.2440828865662129,"score_spread":0.2321546395481757,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}