{"id":"W2126549321","doi":"10.1155/2010/174528","title":"Therapeutic Antibodies Targeting CSF1 Impede Macrophage Recruitment in a Xenograft Model of Tenosynovial Giant Cell Tumor","year":2010,"lang":"en","type":"article","venue":"Sarcoma","topic":"Musculoskeletal synovial abnormalities and treatments","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; University of British Columbia","funders":"Michael Smith Health Research BC; Cancer Research Society; Sarcoma Foundation of America","keywords":"Medicine; Giant cell; Macrophage; Monoclonal antibody; Cancer research; Antibody; Infiltration (HVAC); Pathology; Immunology; In vitro; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003114138,0.0005587017,0.0005496948,0.0003185968,0.0001670304,0.0002569712,0.0003151925,0.0003425157,0.0008356005],"category_scores_gemma":[0.0001650661,0.0001619415,0.0002602929,0.0001553669,0.0002884653,0.0002774262,0.0001195979,0.0007802017,0.00024095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003005888,"about_ca_system_score_gemma":0.0003070511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00131093,"about_ca_topic_score_gemma":0.002265545,"domain_scores_codex":[0.9998288,0.00004551236,0.00001494142,0.00002452324,0.0000407797,0.00004542914],"domain_scores_gemma":[0.9997469,0.00007636335,0.00006089437,0.0000305328,0.00001630828,0.00006900755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004251172,0.0005451834,0.0001043033,0.0000452974,0.000008003531,0.0001064262,0.00003745776,0.0003086216,0.9966091,0.0001606983,0.00009881226,0.001551114],"study_design_scores_gemma":[0.0002239933,0.007942181,0.00166902,0.00001061077,0.00002871454,0.000560611,0.00005436641,0.003573322,0.9840856,0.00007107758,0.001770896,0.000009722406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959055,0.0006991323,0.002099154,0.0001220642,0.00008669227,0.00004797584,0.0001477474,0.0001067384,0.0007849375],"genre_scores_gemma":[0.9944922,0.0007652108,0.002624927,0.00003465626,0.00002188817,0.0000598441,0.0002120497,0.00002338505,0.001765806],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00131093,"threshold_uncertainty_score":0.002795339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02797201796449963,"score_gpt":0.2911283647415704,"score_spread":0.2631563467770708,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}