{"id":"W2126549321","doi":"10.1155/2010/174528","title":"Therapeutic Antibodies Targeting CSF1 Impede Macrophage Recruitment in a Xenograft Model of Tenosynovial Giant Cell Tumor","year":2010,"lang":"en","type":"article","venue":"Sarcoma","topic":"Musculoskeletal synovial abnormalities and treatments","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; University of British Columbia","funders":"Michael Smith Health Research BC; Cancer Research Society; Sarcoma Foundation of America","keywords":"Medicine; Giant cell; Macrophage; Monoclonal antibody; Cancer research; Antibody; Infiltration (HVAC); Pathology; Immunology; In vitro; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002218546,0.0002439553,0.0004604354,0.0001412671,0.00007307388,0.00001442581,0.0001245509,0.00008796014,0.0002080021],"category_scores_gemma":[0.00002417032,0.0001828826,0.0001951903,0.0001586756,0.0001194879,0.00007749499,0.00008856765,0.0003105516,0.0000237856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004866057,"about_ca_system_score_gemma":0.0001043764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007693621,"about_ca_topic_score_gemma":0.0001556393,"domain_scores_codex":[0.9984547,0.0000411419,0.0004702305,0.0002892025,0.0002861326,0.000458609],"domain_scores_gemma":[0.9992957,0.00004361268,0.0001467815,0.0003173859,0.00006023436,0.0001362759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004509544,0.001524883,0.1010223,0.0005503813,0.0001372011,0.0002673565,0.001175122,0.0000287498,0.8768953,0.0009358928,0.00008514147,0.0169267],"study_design_scores_gemma":[0.02190169,0.00347654,0.3354487,0.0006417105,0.0007058592,0.0002223561,0.002144637,0.03134274,0.591256,0.005629963,0.005625898,0.001603915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993081,0.0006734469,0.00006206663,0.0002369675,0.0001718258,0.0008327743,0.00004715593,0.00003982454,0.004854933],"genre_scores_gemma":[0.9951905,0.00007570093,0.003686204,0.0001885948,0.00009504287,0.00005891031,0.00003596395,0.00003557482,0.0006334882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2856393,"threshold_uncertainty_score":0.7457736,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02797201796449963,"score_gpt":0.2911283647415704,"score_spread":0.2631563467770708,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}