{"id":"W2126593792","doi":"10.3390/cancers5020714","title":"Genomic Instability: The Driving Force behind Refractory/Relapsing Hodgkin’s Lymphoma","year":2013,"lang":"en","type":"article","venue":"Cancers","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Université de Sherbrooke","funders":"","keywords":"Genome instability; Oncogene; Cancer research; Biology; Lymphoma; Germinal center; Telomere; Gene expression profiling; Shelterin; BCL6; Chromosome instability; Gene; Gene expression; Transcription factor; Genetics; Cell cycle; Immunology; B cell; DNA damage; DNA; DNA-binding protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001444629,0.0001657836,0.0003493851,0.0003683791,0.0001730819,0.0004856872,0.0001807573,0.0003045239,0.0005295827],"category_scores_gemma":[0.0001679989,0.00007341107,0.0001026058,0.0002617822,0.0003352805,0.0003757286,0.0002256578,0.0003159432,0.0002409779],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003142435,"about_ca_system_score_gemma":0.0001787566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003508964,"about_ca_topic_score_gemma":0.0004011799,"domain_scores_codex":[0.9999307,0.00001303118,0.000008464068,0.00001617874,0.0000185298,0.00001309224],"domain_scores_gemma":[0.9999328,0.0000122565,0.00003077785,0.000003677618,0.000007173504,0.0000134241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009114865,0.00008200437,0.04821037,0.001863293,0.0001378992,0.01204298,0.0009668962,0.001067054,0.5718423,0.005005079,0.00231305,0.3555577],"study_design_scores_gemma":[0.0001482224,0.003881174,0.4615135,0.0009592644,0.0009271266,0.1423251,0.003610868,0.003646237,0.2075554,0.03821133,0.1369818,0.0002399737],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.7916389,0.1967298,0.004538938,0.002233205,0.0001056318,0.00005605625,0.0002741852,0.0002870867,0.004136279],"genre_scores_gemma":[0.9573368,0.04009641,0.0008292311,0.0003329257,0.0001979875,0.00001243758,0.0001358408,0.00001330228,0.001045169],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.0005295827,"threshold_uncertainty_score":0.002280056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01517721046342889,"score_gpt":0.2514988695925404,"score_spread":0.2363216591291115,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}