{"id":"W2126608512","doi":"10.1007/s10858-013-9705-2","title":"Probing non-specific interactions of Ca2+-calmodulin in E. coli lysate","year":2013,"lang":"en","type":"article","venue":"Journal of Biomolecular NMR","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs; National Science Foundation","keywords":"Calmodulin; Lysis; Chemistry; Escherichia coli; Dissociation constant; Function (biology); Biophysics; Nuclear magnetic resonance spectroscopy; Dissociation (chemistry); Relaxation (psychology); Biochemistry; Stereochemistry; Cell biology; Biology; Enzyme; Gene; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001656536,0.0001198944,0.0002146098,0.0001527659,0.00002338321,0.00002139913,0.0002087529,0.0001047832,0.00002813132],"category_scores_gemma":[0.00003606725,0.0001040472,0.000156974,0.0001657835,0.00005925031,0.00001248033,0.00006712407,0.0001652102,0.000005883451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002730348,"about_ca_system_score_gemma":0.00006558019,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003269715,"about_ca_topic_score_gemma":0.00001612976,"domain_scores_codex":[0.9990146,0.00005224642,0.0004830791,0.0001357775,0.0001443878,0.0001699532],"domain_scores_gemma":[0.9991413,0.000007375704,0.0003328279,0.0002186515,0.0002262433,0.00007362339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005212109,0.00006231992,0.0003684527,0.00001600835,0.0000494495,0.00002331665,0.00006335601,0.0001392561,0.9949812,0.00003562651,0.0004518984,0.00375695],"study_design_scores_gemma":[0.001162896,0.000462334,0.006914076,0.0001341679,0.00002162947,0.0002708425,0.0001558415,0.000572545,0.9819869,0.0006309582,0.007468341,0.0002194981],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9768413,0.0006410003,0.02151467,0.0001700882,0.0001854209,0.0001867341,0.000004104471,0.000001795139,0.000454899],"genre_scores_gemma":[0.994714,0.0001732683,0.004786813,0.00009718959,0.0001336945,0.000005463954,0.000008491217,0.00001631569,0.00006482031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01787265,"threshold_uncertainty_score":0.4242923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006717825843978627,"score_gpt":0.242185970444855,"score_spread":0.2354681446008764,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}