{"id":"W2126609076","doi":"10.1016/j.ibmb.2007.03.005","title":"Characterization of Aedes Dredd: A novel initiator caspase from the yellow fever mosquito, Aedes aegypti","year":2007,"lang":"en","type":"article","venue":"Insect Biochemistry and Molecular Biology","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; Agriculture and Agri-Food Canada; Simon Fraser University","funders":"Michael Smith Health Research BC","keywords":"Biology; Aedes aegypti; Caspase; Innate immune system; Effector; Drosophila melanogaster; Cell biology; Proteases; Aedes; Programmed cell death; Apoptosis; Virology; Gene; Genetics; Immune system; Biochemistry; Enzyme; Dengue fever","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002602491,0.0002747974,0.0002395234,0.00003307412,0.0001149338,0.00002238188,0.0002865075,0.0004557779,0.00002058207],"category_scores_gemma":[0.0001327211,0.0002268861,0.0001268456,0.0001274717,0.0004075657,0.000004256739,0.0001644097,0.0001471609,0.000001897233],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001315611,"about_ca_system_score_gemma":0.0001032916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009863245,"about_ca_topic_score_gemma":0.00008085553,"domain_scores_codex":[0.9985939,0.00005556459,0.0003714019,0.0005053632,0.0001117454,0.0003620194],"domain_scores_gemma":[0.9989977,0.00004504539,0.0002008675,0.0005157175,0.0001393024,0.0001013027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001916659,0.00007390156,0.002659834,0.00003174844,0.0001215732,0.00001260255,0.00007257757,0.00000120119,0.995746,0.000101634,0.00006096633,0.0009263452],"study_design_scores_gemma":[0.0005838204,0.0001452203,0.005552928,0.0000277154,0.00005053498,0.00003716088,0.00008308113,0.000005698751,0.9880678,0.0001004366,0.005074135,0.0002714748],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879031,0.001786075,0.009139271,0.0001475824,0.0001423447,0.0001788091,0.0002920215,0.00001298311,0.0003977957],"genre_scores_gemma":[0.9963518,0.0003287984,0.0007942102,0.001069203,0.0003418108,0.00001420951,0.0009778867,0.00002804441,0.0000940023],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008448717,"threshold_uncertainty_score":0.9252148,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009620299956465093,"score_gpt":0.24767778209439,"score_spread":0.2380574821379249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}