{"id":"W2126612251","doi":"10.1139/o09-161","title":"Structural disorder and dynamics of elastinThis paper is one of a selection of papers published in this special issue entitled “Canadian Society of Biochemistry, Molecular &amp; Cellular Biology 52nd Annual Meeting — Protein Folding: Principles and Diseases” and has undergone the Journal's usual peer review process.","year":2010,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":156,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Australian Research Council; Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Elastin; Elastic recoil; Conformational entropy; Extracellular matrix; Molecular dynamics; Biophysics; Computational biology; Chemistry; Neuroscience; Cognitive science; Biochemistry; Biology; Psychology; Genetics; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007115843,0.0004008146,0.001086171,0.00009084999,0.0001091816,0.00001969209,0.0002927517,0.0008453392,0.0007376749],"category_scores_gemma":[0.0007938762,0.0003198754,0.0001913566,0.0002515614,0.001302779,0.00001087345,0.000274607,0.0005113782,9.056352e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003419881,"about_ca_system_score_gemma":0.0006631276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007158965,"about_ca_topic_score_gemma":0.0007565144,"domain_scores_codex":[0.9978231,0.0002311982,0.00080289,0.0006067085,0.0001884019,0.0003477042],"domain_scores_gemma":[0.9981195,0.00008733544,0.0007991089,0.0003082101,0.000523451,0.0001623745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001060609,0.0001175286,0.002255595,0.03534259,0.00042736,9.173095e-7,0.0002041372,4.373088e-7,0.9051147,0.00002374489,0.0002744729,0.05613245],"study_design_scores_gemma":[0.001891879,0.0008177164,0.0001218499,0.006313809,0.001187952,0.0001077635,0.0009314343,0.00005582387,0.5373049,0.0002440585,0.449896,0.001126813],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2535722,0.7446835,0.000008899966,0.000325843,0.00003000743,0.0005814877,0.0005023252,0.000002004417,0.0002937365],"genre_scores_gemma":[0.1342582,0.8641046,0.0001778294,0.00002327113,0.0001718791,0.00003530043,0.0007628208,0.00003642831,0.0004297731],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.4496215,"threshold_uncertainty_score":0.9999253,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01671925104311428,"score_gpt":0.2847415080917604,"score_spread":0.2680222570486461,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}