{"id":"W2126629462","doi":"10.1677/jme.1.02052","title":"Cyclosporin A inhibits apolipoprotein AI gene expression","year":2006,"lang":"en","type":"article","venue":"Journal of Molecular Endocrinology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Calcineurin; Apolipoprotein B; Gene expression; Transfection; Calcium in biology; Chemistry; Reporter gene; Hyperlipidemia; Molecular biology; Intracellular; Endocrinology; Biology; Gene; Internal medicine; Cholesterol; Biochemistry; Medicine; Transplantation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001084984,0.0002397518,0.0001983027,0.0002846311,0.0001580094,0.0002790789,0.0001524609,0.0001910447,0.001044894],"category_scores_gemma":[0.0001649872,0.00006467122,0.0001624347,0.0001912832,0.0002438021,0.00008032097,0.0001083542,0.0005503603,0.0003021392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003314679,"about_ca_system_score_gemma":0.0003916602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000760234,"about_ca_topic_score_gemma":0.001268229,"domain_scores_codex":[0.9998788,0.0000240192,0.00001160483,0.00001967898,0.00003550946,0.000030384],"domain_scores_gemma":[0.9998081,0.0000535078,0.00003971318,0.00002501812,0.00002268543,0.00005101155],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001421247,0.00007245521,0.000230651,0.00003325001,0.000006011008,0.00003678623,0.000008701381,0.00005275831,0.9960713,0.0001595462,0.0001191177,0.003067236],"study_design_scores_gemma":[0.00005765951,0.0005966101,0.00484293,0.000006913102,0.00001417658,0.0001731381,0.00001645819,0.000997102,0.9883134,0.00005845843,0.0049198,0.000003405428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907829,0.002454903,0.001896601,0.0002531889,0.0001074812,0.00003976239,0.0002769602,0.0002225669,0.003965528],"genre_scores_gemma":[0.9920737,0.002138444,0.001208881,0.00008129897,0.00004309994,0.00004485121,0.0003999429,0.00002281784,0.003986902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001044894,"threshold_uncertainty_score":0.003495514,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005654082457350862,"score_gpt":0.2394437849936203,"score_spread":0.2337897025362695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}