{"id":"W2126629462","doi":"10.1677/jme.1.02052","title":"Cyclosporin A inhibits apolipoprotein AI gene expression","year":2006,"lang":"en","type":"article","venue":"Journal of Molecular Endocrinology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Calcineurin; Apolipoprotein B; Gene expression; Transfection; Calcium in biology; Chemistry; Reporter gene; Hyperlipidemia; Molecular biology; Intracellular; Endocrinology; Biology; Gene; Internal medicine; Cholesterol; Biochemistry; Medicine; Transplantation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001447794,0.0002115009,0.0002690667,0.0001234497,0.000049774,0.00001855875,0.0003564332,0.0001641383,0.00002808491],"category_scores_gemma":[0.0001437384,0.000197046,0.0002593802,0.00009725625,0.0001019589,0.000006512654,0.0001579559,0.0002564289,0.00001135316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000287122,"about_ca_system_score_gemma":0.0001474817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000211052,"about_ca_topic_score_gemma":0.000003614402,"domain_scores_codex":[0.9983539,0.0001510359,0.0005337715,0.0002751251,0.0002740059,0.0004121652],"domain_scores_gemma":[0.9988704,0.000009736554,0.0003661154,0.0003858871,0.0002403587,0.000127494],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001979446,0.0001572321,0.001538134,0.00001092837,0.00004874686,0.0006884817,0.000005632019,0.0007208376,0.9925666,0.0002748203,0.002955993,0.0008346131],"study_design_scores_gemma":[0.001249454,0.000398178,0.0005152755,0.00002699773,0.00003700765,0.001208775,0.000009703802,0.000003686329,0.983398,0.001273529,0.01168773,0.0001916294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9809694,0.004329952,0.01335495,0.0004470346,0.0003097184,0.0001260422,0.000009093851,0.00001260801,0.0004412319],"genre_scores_gemma":[0.9939161,0.00006401631,0.004532714,0.0005378865,0.0007354916,0.000009859567,0.00002568654,0.00003960506,0.0001386706],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0129467,"threshold_uncertainty_score":0.8035302,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005654082457350862,"score_gpt":0.2394437849936203,"score_spread":0.2337897025362695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}