{"id":"W2126663323","doi":"10.3899/jrheum.080071","title":"Functional Polymorphisms of Folate-Metabolizing Enzymes in Relation to Homocysteine Concentrations in Systemic Lupus Erythematosus","year":2008,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Research Resources; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Environmental Health Sciences; Lupus Research Institute; National Institutes of Health; Georgia Clinical and Translational Science Alliance; Lupus Research Alliance","keywords":"Methylenetetrahydrofolate reductase; Homocysteine; MTRR; Cystathionine beta synthase; Methionine synthase; Internal medicine; Medicine; Genotype; Endocrinology; Methionine; Genetics; Biology; Gene; Amino acid","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007247277,0.00009160368,0.0005105378,0.0005473909,0.00004972415,0.000002676461,0.0001128068,0.00009127587,0.00005543016],"category_scores_gemma":[0.0002775131,0.00006113826,0.00007094534,0.000493749,0.0001003603,0.000105628,0.00002806543,0.000341906,0.00001693346],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008812659,"about_ca_system_score_gemma":0.0002710157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000292411,"about_ca_topic_score_gemma":0.0001182937,"domain_scores_codex":[0.9983605,0.0002110145,0.0008294873,0.00007869342,0.000305786,0.0002145898],"domain_scores_gemma":[0.9989796,0.0003242283,0.000277006,0.0001533853,0.0001890631,0.00007671014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001131809,0.0001447083,0.9650682,0.00006962511,0.00007849967,0.0001098651,0.002603484,0.0004933405,0.025997,0.003497844,0.0006277147,0.0001779562],"study_design_scores_gemma":[0.01032363,0.001420251,0.6646237,0.001852826,0.0001117768,0.3080557,0.00251223,0.001043447,0.009183759,0.0004784546,0.0001996517,0.0001945832],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920427,0.00586484,0.000387625,0.001103333,0.0002651537,0.0002144781,0.000001519486,0.000004492351,0.0001158775],"genre_scores_gemma":[0.9984015,0.001211784,0.0001507586,0.00003353135,0.00001294348,0.000003230955,0.00000218288,0.000009987407,0.0001740356],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3079458,"threshold_uncertainty_score":0.2493146,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02791270115469763,"score_gpt":0.2729999158234953,"score_spread":0.2450872146687976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}