{"id":"W2126775563","doi":"10.1534/genetics.114.171124","title":"Too Much of a Good Thing: The Unique and Repeated Paths Toward Copper Adaptation","year":2014,"lang":"en","type":"article","venue":"Genetics","topic":"Trace Elements in Health","field":"Nursing","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Killam Trusts","keywords":"Biology; Genetics; Gene; Copper deficiency; Mutation; Saccharomyces cerevisiae; Adaptation (eye); Phenotype; Micronutrient; Gene duplication; Metallothionein; Copper","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004114185,0.00007869653,0.0001024456,0.00002789769,0.00007738031,0.00001735012,0.0001035172,0.00006548743,0.000006595651],"category_scores_gemma":[0.0001149409,0.00006130624,0.00001748515,0.00008361558,0.00005432406,0.00002385323,0.00003222445,0.0001135579,0.000002786957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002626978,"about_ca_system_score_gemma":0.00002563002,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008045169,"about_ca_topic_score_gemma":0.00008948809,"domain_scores_codex":[0.9991227,0.0001764022,0.0002313319,0.0001435186,0.0001654293,0.0001605704],"domain_scores_gemma":[0.9993625,0.0001333868,0.0001136874,0.0002746958,0.00007561684,0.00004015048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003861672,0.0003505126,0.09216177,0.0007098766,0.0001198502,0.000003279608,0.1186443,0.003527344,0.06074961,0.01235812,0.01486818,0.696121],"study_design_scores_gemma":[0.004976169,0.004467488,0.3367253,0.0004013076,0.0003982195,0.00006243148,0.01584318,0.1086789,0.3458416,0.02328856,0.1581513,0.001165489],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920266,0.0003786095,0.002675118,0.003147456,0.0003826944,0.0003180004,0.00000724662,0.0000426221,0.001021632],"genre_scores_gemma":[0.9888549,0.00005680653,0.01038808,0.0005591631,0.00006636931,0.00000606531,0.000005649967,0.00001679142,0.0000461994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6949555,"threshold_uncertainty_score":0.2499996,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0328211744415452,"score_gpt":0.2877426868302129,"score_spread":0.2549215123886677,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}