{"id":"W2126875247","doi":"10.1002/bit.22647","title":"Influence of substrate stiffness on the phenotype of heart cells","year":2009,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":376,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Heart, Lung, and Blood Institute","keywords":"Stiffness; Elongation; Staining; Biophysics; Biomedical engineering; Materials science; Chemistry; Substrate (aquarium); Troponin I; Composite material; Ultimate tensile strength; Medicine; Pathology; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002161791,0.0002679481,0.0001723096,0.0001091385,0.0001175289,0.000417847,0.00008866406,0.0002053236,0.0010244],"category_scores_gemma":[0.0004385518,0.0001567825,0.0001176925,0.000120235,0.0001487022,0.0001916406,0.0002507257,0.0002490126,0.0001805329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001290592,"about_ca_system_score_gemma":0.0001097135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003424586,"about_ca_topic_score_gemma":0.0008155156,"domain_scores_codex":[0.9997794,0.00006158615,0.00002836524,0.0000386345,0.00005256501,0.00003942295],"domain_scores_gemma":[0.9995118,0.0002756915,0.0000736811,0.00003559432,0.00005027701,0.00005291646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009050802,0.000009286289,0.0006188771,0.00002869543,0.000004432825,0.00005238942,0.00002578699,0.00008194368,0.9984447,0.00001174383,0.00001011692,0.0006215933],"study_design_scores_gemma":[0.00001442724,0.0004332945,0.03602016,0.00001412072,0.00002584784,0.0002837824,0.0001418162,0.001103791,0.9611849,0.00002342366,0.0007421324,0.00001214539],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979893,0.0006064218,0.0004676508,0.0000229262,0.00000949641,0.000007014646,0.00008124496,0.000007113683,0.000808791],"genre_scores_gemma":[0.9978224,0.0005319808,0.0008269902,0.00003879353,0.000004873013,0.00001744762,0.0001338148,0.000007230537,0.0006165508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0010244,"threshold_uncertainty_score":0.003426969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009541504105293608,"score_gpt":0.2248237671736628,"score_spread":0.2152822630683692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}