{"id":"W2126904458","doi":"10.1242/dmm.019257","title":"The putative tumor suppressor gene<i>EphA3</i>fails to demonstrate a crucial role in murine lung tumorigenesis or morphogenesis","year":2015,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Biology; Mesenchyme; Carcinogenesis; Cancer research; Phenotype; Lung cancer; CD31; KRAS; Suppressor; Tumor suppressor gene; Cell biology; Mesenchymal stem cell; Gene; Genetics; Pathology; Angiogenesis; Mutation; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002381207,0.000422546,0.0002362892,0.0003512782,0.000231918,0.0003374057,0.0002921213,0.000521074,0.00219553],"category_scores_gemma":[0.0001678802,0.0001970461,0.0004617223,0.0001371143,0.0005707396,0.0003036917,0.0002693053,0.001044952,0.0008197543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003471907,"about_ca_system_score_gemma":0.0003507912,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000583428,"about_ca_topic_score_gemma":0.000954167,"domain_scores_codex":[0.9996984,0.00005403944,0.00003941788,0.00007015594,0.00008263584,0.00005541662],"domain_scores_gemma":[0.9996365,0.0000867989,0.0001112308,0.00007303528,0.00002265481,0.00006982966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004800415,0.00001667533,0.0001285359,0.00001562991,0.00000354298,0.00003822053,0.00000523251,0.00003846446,0.9990587,0.0001552665,0.00001882431,0.000472915],"study_design_scores_gemma":[0.000009166231,0.0001857729,0.001923054,0.000006006273,0.00001210008,0.0005007868,0.00001500562,0.0005362949,0.9944336,0.00007412355,0.002301612,0.000002504928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854693,0.0009440446,0.009749964,0.0002717042,0.00006830684,0.00004221495,0.001072278,0.0003100356,0.002072285],"genre_scores_gemma":[0.9885418,0.0005803276,0.005380047,0.0001244411,0.00001317403,0.00005692917,0.001222009,0.0001952873,0.003885923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00219553,"threshold_uncertainty_score":0.007344782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02172945625576183,"score_gpt":0.2582410040786545,"score_spread":0.2365115478228927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}