{"id":"W2126906371","doi":"10.1021/ja406025p","title":"A Pd(0)-Catalyzed Direct Dehydrative Coupling of Terminal Alkynes with Allylic Alcohols To Access 1,4-Enynes","year":2013,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Chinese Academy of Sciences; Canada Research Chairs; McGill University","keywords":"Chemistry; Allylic rearrangement; Catalysis; Coupling (piping); Terminal (telecommunication); Combinatorial chemistry; Ligand (biochemistry); Coupling reaction; Palladium; Medicinal chemistry; Organic chemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003194684,0.0002208513,0.0006075406,0.00002999737,0.00008382277,0.00007646436,0.0008139596,0.00006073929,0.0003913292],"category_scores_gemma":[0.0005016471,0.000137707,0.0004844448,0.0006321943,0.0005003721,0.0002471819,0.0002637822,0.0003448506,0.000004131984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001999323,"about_ca_system_score_gemma":0.0001894517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001626823,"about_ca_topic_score_gemma":0.000002112995,"domain_scores_codex":[0.9982179,0.00001967253,0.0006145877,0.0002264358,0.0006658241,0.0002555696],"domain_scores_gemma":[0.9969603,0.000575146,0.001334959,0.0003595158,0.0005825687,0.000187544],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001352264,0.0001091711,0.008945595,0.00005027199,0.0003941244,0.000001591799,0.0005457779,0.0006818174,0.9843895,0.000003895395,0.003807431,0.0009355366],"study_design_scores_gemma":[0.000583264,0.00004572212,0.00404904,0.0001820326,0.0002223074,0.0001209466,0.0009518751,0.001078845,0.9916731,0.0001083421,0.0007550984,0.0002294636],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961557,0.00005231301,0.001820489,0.001295884,0.00005672478,0.0001098901,0.0000143559,0.00001800879,0.0004766607],"genre_scores_gemma":[0.9880326,0.0000201847,0.01073214,0.0005490406,0.0003109384,0.00002004,0.00000508318,0.00003344793,0.0002964769],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008911651,"threshold_uncertainty_score":0.561553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02145827727746534,"score_gpt":0.3137580564434881,"score_spread":0.2922997791660228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}