{"id":"W2126912388","doi":"10.1046/j.1365-2958.2000.01981.x","title":"Site‐specific DNA binding and bending by the <i>Borrelia burgdorferi</i> Hbb protein","year":2000,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Vector-borne infectious diseases","field":"Immunology and Microbiology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Medical Research Council; Medical Research Council Canada","keywords":"Biology; DnaA; DNA supercoil; DNA; DNA footprinting; Borrelia burgdorferi; DNA replication; Plasmid; Molecular biology; HMG-box; Gene; Genetics; Prokaryotic DNA replication; DNA-binding protein; Escherichia coli; DNA binding site; Origin of replication; Promoter; Transcription factor; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002153307,0.0003669402,0.0003699425,0.0000995813,0.0004561968,0.0000511663,0.0003303747,0.000398774,0.002767524],"category_scores_gemma":[0.0000341487,0.0002901326,0.0001419026,0.0002075111,0.0006270268,0.00005253197,0.0001306611,0.000444166,0.001829571],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006442424,"about_ca_system_score_gemma":0.00003249244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000941613,"about_ca_topic_score_gemma":0.00001372252,"domain_scores_codex":[0.9977791,0.0004769233,0.0003510755,0.0006596051,0.00002239384,0.0007108855],"domain_scores_gemma":[0.99922,0.00009676167,0.0001085022,0.0004877734,0.00004081599,0.0000461903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008101742,0.00008634327,0.0005519118,0.000008999125,0.0001430361,0.00002694132,0.0001035278,0.000002485858,0.9755298,0.0004326974,0.01919048,0.003842784],"study_design_scores_gemma":[0.0007975867,0.0001566663,0.0001906582,0.00002290071,0.00004673645,0.0006421625,0.00003376358,4.719345e-7,0.5612761,0.00005046914,0.436481,0.0003014633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804143,0.01605828,0.00006423313,0.0004856378,0.000321952,0.0005932215,0.0002635431,0.0001683969,0.001630449],"genre_scores_gemma":[0.9946482,0.000214099,0.00003249491,0.0008559797,0.00003402304,0.00008873721,0.0005825157,0.00005241108,0.003491522],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4172905,"threshold_uncertainty_score":0.9999551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004287323670191157,"score_gpt":0.1921731699297468,"score_spread":0.1878858462595556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}