{"id":"W2127016965","doi":"10.1182/blood.v97.11.3581","title":"Primary chromosomal rearrangements of leukemia are frequently accompanied by extensive submicroscopic deletions and may lead to altered prognosis","year":2001,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":217,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research","funders":"","keywords":"Breakpoint; Haploinsufficiency; Biology; Chromosomal translocation; breakpoint cluster region; Myeloid leukemia; Leukemia; Fluorescence in situ hybridization; Comparative genomic hybridization; Genetics; Cytogenetics; Gene rearrangement; Molecular biology; Chromosome; Cancer research; Gene; Phenotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001385895,0.0001982937,0.0002693184,0.0003625161,0.0001533907,0.0001806343,0.00008126173,0.0001755806,0.002541909],"category_scores_gemma":[0.0005768935,0.0000659234,0.00009779351,0.0003122762,0.0001712984,0.0001056659,0.000233972,0.0001357854,0.0005999552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001592316,"about_ca_system_score_gemma":0.00008676201,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002410417,"about_ca_topic_score_gemma":0.0003343277,"domain_scores_codex":[0.9999034,0.00001324598,0.000007143543,0.00002028972,0.00002368733,0.00003216105],"domain_scores_gemma":[0.99962,0.00004460253,0.0001720566,0.00003531273,0.00003523885,0.00009274165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001370666,0.00007971244,0.8005819,0.0001086956,0.00007291493,0.01228391,0.000131092,0.0004421074,0.1231827,0.0003292406,0.0009280471,0.06048891],"study_design_scores_gemma":[0.00001014854,0.0002731278,0.9688538,0.000008056008,0.00002591564,0.02342084,0.00004350322,0.0002315235,0.004702734,0.000270919,0.002152484,0.000006875414],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961686,0.001469813,0.0007195127,0.0000391102,0.000009390852,0.00001121491,0.0002758295,0.00007864843,0.001227942],"genre_scores_gemma":[0.9989624,0.0002990698,0.0001752655,0.0000104349,0.00001248977,0.000003620523,0.000226414,0.000004420028,0.0003058224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002541909,"threshold_uncertainty_score":0.008503497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01840919972254899,"score_gpt":0.26336061842172,"score_spread":0.244951418699171,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}