{"id":"W2127161069","doi":"10.1261/rna.2184010","title":"A group II intron encodes a functional LAGLIDADG homing endonuclease and self-splices under moderate temperature and ionic conditions","year":2010,"lang":"en","type":"article","venue":"RNA","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Centre National de la Recherche Scientifique; University of Manitoba; Manitoba Health Research Council","keywords":"Intron; Biology; Homing endonuclease; Group II intron; RNA splicing; Ribozyme; Open reading frame; RNA; Group I catalytic intron; Genetics; Endonuclease; Gene; Molecular biology; Peptide sequence","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000107966,0.0003849964,0.000178683,0.000112802,0.00009907239,0.0002384023,0.0001483634,0.0002006673,0.0004968861],"category_scores_gemma":[0.000147571,0.00009578019,0.0001939114,0.00009407212,0.0001897947,0.0001043974,0.0001201171,0.0002627724,0.0004723899],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001816209,"about_ca_system_score_gemma":0.0001476428,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001841951,"about_ca_topic_score_gemma":0.0002970171,"domain_scores_codex":[0.9999313,0.000006606869,0.00000549001,0.00002328576,0.00002033677,0.00001290949],"domain_scores_gemma":[0.9998468,0.000025919,0.00005255613,0.00002241054,0.00001657121,0.00003567723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002505742,0.000004665784,0.0003734937,0.000007622915,0.000001164912,0.00004801533,0.000009716617,0.00001514855,0.9986455,0.00006882019,0.000009426456,0.000791479],"study_design_scores_gemma":[0.00001146619,0.0001788879,0.01076097,0.000006890883,0.00001261469,0.0008478425,0.00004253534,0.0006407988,0.9838552,0.0001406607,0.00349751,0.000004604984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913499,0.0002865645,0.00716695,0.00002815416,0.00001921661,0.00001721121,0.0001424291,0.00007432433,0.000915033],"genre_scores_gemma":[0.9892561,0.0001630847,0.006484507,0.00002903654,0.00001157857,0.00001960754,0.001186824,0.000035492,0.002813741],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004968861,"threshold_uncertainty_score":0.001662254,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005060944155990688,"score_gpt":0.207516353750332,"score_spread":0.2024554095943413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}