{"id":"W2127161069","doi":"10.1261/rna.2184010","title":"A group II intron encodes a functional LAGLIDADG homing endonuclease and self-splices under moderate temperature and ionic conditions","year":2010,"lang":"en","type":"article","venue":"RNA","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Centre National de la Recherche Scientifique; University of Manitoba; Manitoba Health Research Council","keywords":"Intron; Biology; Homing endonuclease; Group II intron; RNA splicing; Ribozyme; Open reading frame; RNA; Group I catalytic intron; Genetics; Endonuclease; Gene; Molecular biology; Peptide sequence","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001016395,0.0001203629,0.00009272966,0.00002820192,0.0003163106,0.00006793473,0.00004965296,0.0001603856,0.00006084126],"category_scores_gemma":[0.00001942954,0.0001070275,0.00003091032,0.00002779676,0.0000531296,0.0000104135,0.00007353206,0.000118394,0.000002750008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000371517,"about_ca_system_score_gemma":0.00002766129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001023256,"about_ca_topic_score_gemma":0.00005298708,"domain_scores_codex":[0.9994071,0.00003173867,0.00008995916,0.000263172,0.00006653943,0.000141567],"domain_scores_gemma":[0.9996901,0.00001357948,0.00003971958,0.0001415431,0.00002999887,0.00008507897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004316538,0.00004153559,0.00005577758,0.00001177469,0.00003693263,0.0000014891,0.00004490455,0.000006659633,0.9942269,0.004726765,0.0001572046,0.0006468603],"study_design_scores_gemma":[0.0007610656,0.0002864503,0.00252716,0.00002297311,0.0000587938,0.0001266719,0.000153059,0.0003415041,0.9840872,0.00507743,0.006229163,0.0003285341],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982617,0.0005806607,0.0003652392,0.0002872351,0.0001112939,0.0001260573,0.00002457539,0.00002065723,0.000222506],"genre_scores_gemma":[0.9974986,0.000201671,0.001413123,0.0002817158,0.0002492528,0.00003704454,0.00004831078,0.00001518562,0.0002550656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01013973,"threshold_uncertainty_score":0.4364454,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005060944155990688,"score_gpt":0.207516353750332,"score_spread":0.2024554095943413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}