{"id":"W2127229183","doi":"10.3899/jrheum.130263","title":"Longterm Safety, Efficacy, and Inhibition of Structural Damage Progression Over 5 Years of Treatment with Abatacept in Patients with Rheumatoid Arthritis in the Abatacept in Inadequate Responders to Methotrexate Trial","year":2014,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta Hospital; Alberta Hospital Edmonton","funders":"Versus Arthritis; National Institute for Health and Care Research","keywords":"Medicine; Abatacept; Rheumatoid arthritis; Internal medicine; Discontinuation; Methotrexate; Rheumatology; Leflunomide; Adverse effect; Placebo; Incidence (geometry); Gastroenterology; Surgery; Rituximab","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002594431,0.0004621672,0.001157244,0.0001969297,0.0003046888,0.0005964694,0.0003916544,0.0007983053,0.001313111],"category_scores_gemma":[0.001724117,0.0001769026,0.001060756,0.0002082319,0.0002596512,0.0004769046,0.0002287053,0.001281852,0.0002339292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000312744,"about_ca_system_score_gemma":0.0003699315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005188581,"about_ca_topic_score_gemma":0.001291285,"domain_scores_codex":[0.9993343,0.0003714004,0.00006328849,0.00007749596,0.00007322442,0.00008032747],"domain_scores_gemma":[0.9984169,0.0003678512,0.0006467516,0.00009444106,0.00009829958,0.0003757405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.849324,0.007457905,0.05182144,0.001029244,0.003273011,0.0001923745,0.0001781699,0.0008923229,0.00688528,0.00008862129,0.001472216,0.07738537],"study_design_scores_gemma":[0.3382731,0.3522742,0.2975339,0.0003217548,0.003618729,0.0006199463,0.0001273515,0.002364899,0.001729702,0.0002456803,0.002832341,0.00005834061],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937682,0.004964506,0.00009062843,0.0001728819,0.00005679924,0.0001061147,0.0002402107,0.00001274053,0.0005879585],"genre_scores_gemma":[0.997674,0.0009783243,0.0001666855,0.0002453995,0.0001220763,0.0001264027,0.0003158002,0.000002004192,0.0003692249],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002594431,"threshold_uncertainty_score":0.01372081,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01017407320470232,"score_gpt":0.2818831785991134,"score_spread":0.2717091053944111,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}