{"id":"W2127332380","doi":"10.1128/jvi.06561-11","title":"Anti-HIV-1 Activity of Elafin Is More Potent than Its Precursor's, Trappin-2, in Genital Epithelial Cells","year":2012,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Public Health Agency of Canada; McMaster University","funders":"","keywords":"Elafin; Biology; Recombinant DNA; Receptor; Endogeny; CXCR4; Human immunodeficiency virus (HIV); Virology; Molecular biology; Immunology; Chemokine; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001437229,0.0002257265,0.0001976645,0.0001249185,0.0001129486,0.0003722182,0.0001230947,0.0001913882,0.001055778],"category_scores_gemma":[0.0001166102,0.00007121418,0.0002441024,0.0001158416,0.0001011693,0.0001776711,0.0001758892,0.0003949384,0.0002233595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001293371,"about_ca_system_score_gemma":0.0001240542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003652147,"about_ca_topic_score_gemma":0.0004591914,"domain_scores_codex":[0.9998468,0.00002724788,0.00001666505,0.00003116854,0.00004239774,0.00003560405],"domain_scores_gemma":[0.9999299,0.0000207738,0.00001173183,0.00001259168,0.0000113692,0.00001366848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005355265,0.00002148351,0.0001784525,0.00002894969,0.000004798911,0.00002953617,0.00001228812,0.00001572895,0.9986404,0.00001860286,0.00002347794,0.000972844],"study_design_scores_gemma":[0.00001139069,0.0003176906,0.008933688,0.000005570319,0.00001316057,0.0003917917,0.00003360966,0.000366524,0.9881268,0.00001169129,0.001785651,0.000002491935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963647,0.001683939,0.0007469186,0.00006567266,0.00001542267,0.00001136454,0.0002678472,0.00001923548,0.0008249067],"genre_scores_gemma":[0.9960498,0.0006886409,0.0008384204,0.0000588428,0.00001252306,0.00001752173,0.0007290476,0.000004977546,0.001600246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001055778,"threshold_uncertainty_score":0.003531933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01740948211200941,"score_gpt":0.2723576843178291,"score_spread":0.2549482022058197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}