{"id":"W2127372364","doi":"10.1158/1535-7163.mct-07-0329","title":"Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of Integrin-linked kinase (ILK)","year":2008,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; QLT (Canada); University of British Columbia","funders":"","keywords":"Integrin-linked kinase; Protein kinase B; Angiogenesis; Apoptosis; Cell growth; Cancer research; CD31; DAPI; In vivo; Chemistry; Cell cycle; Flow cytometry; Biology; Molecular biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001066058,0.0001504671,0.0002816566,0.000187083,0.00002585754,0.000003146927,0.00005506655,0.0001297435,0.00007583019],"category_scores_gemma":[0.00001057753,0.0001362951,0.0000541111,0.0001922078,0.0002190055,0.00002918986,0.00007145336,0.0002127776,0.000001530333],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000136344,"about_ca_system_score_gemma":0.00005211217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001456719,"about_ca_topic_score_gemma":0.00004622422,"domain_scores_codex":[0.9987896,0.00007968533,0.0002782192,0.0002382898,0.0004037672,0.0002104033],"domain_scores_gemma":[0.9994791,0.00002351375,0.0001165653,0.0002328524,0.00006807668,0.00007989278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000680045,0.0002529771,0.004882578,0.0002050246,0.0000363998,0.00006945125,0.0007542213,0.00001787096,0.9850987,0.000005216618,0.00003531742,0.007962166],"study_design_scores_gemma":[0.002184421,0.0006598905,0.01046797,0.0003360556,0.00003937254,0.00002371823,0.0001308859,0.0008718696,0.98351,0.00001874654,0.001649734,0.000107379],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942419,0.004108647,0.0004617632,0.0006197566,0.00002739215,0.0004603727,0.00002856656,0.000009391553,0.00004224552],"genre_scores_gemma":[0.9931852,0.006047374,0.0002928134,0.000272411,0.00001164659,0.00003928371,0.00003260716,0.00002992429,0.00008872086],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007854788,"threshold_uncertainty_score":0.5557954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02297526227074939,"score_gpt":0.2869428067990933,"score_spread":0.263967544528344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}