{"id":"W2127398275","doi":"10.1093/abbs/36.1.16","title":"DNAskew: Statistical Analysis of Base Compositional Asymmetry and Prediction of Replication Boundaries in the Genome Sequences","year":2004,"lang":"en","type":"article","venue":"Acta Biochimica et Biophysica Sinica","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Gary Bennett Family Fund","keywords":"Perl; Genome; Genetics; Biology; Replication (statistics); GenBank; Codon usage bias; Origin of replication; Phylogenetic tree; DNA replication; Replication timing; Computational biology; Gene; Computer science; Programming language","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003890831,0.00011258,0.0002246819,0.0001024591,0.00007111386,0.00002940305,0.0001930783,0.00009503069,0.000005908844],"category_scores_gemma":[0.0001141643,0.00008779983,0.00009089759,0.0003349184,0.0004325774,0.000008945531,0.00005267852,0.00006624286,4.388095e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009451969,"about_ca_system_score_gemma":0.00009811487,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009977623,"about_ca_topic_score_gemma":0.0000189382,"domain_scores_codex":[0.9989018,0.0001155133,0.0003497349,0.000337684,0.0001825643,0.0001126363],"domain_scores_gemma":[0.9991593,0.00008527503,0.0002003887,0.0004619857,0.00006089551,0.00003217135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001001885,0.0001858507,0.0001639679,0.00001652696,0.0001873884,4.890642e-7,0.0002006673,0.0000218936,0.9914435,0.007474339,0.00001299902,0.0001921829],"study_design_scores_gemma":[0.0003163287,0.0005062455,0.1327857,0.00001897376,0.0002572078,0.000004565349,0.00009112908,0.00004847911,0.8627641,0.002654372,0.0004420624,0.0001108359],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951915,0.0001160665,0.002113529,0.001490232,0.00001853804,0.000175094,0.0007707212,0.000004571358,0.000119755],"genre_scores_gemma":[0.9950639,0.0001512603,0.003639672,0.0002376446,0.00003109273,0.00002070417,0.0008449937,0.000007145,0.000003563566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1326217,"threshold_uncertainty_score":0.3580373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01413899695279542,"score_gpt":0.2675347691975573,"score_spread":0.2533957722447618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}