{"id":"W2127399131","doi":"10.1093/molehr/gap083","title":"Genomic changes detected by array CGH in human embryos with developmental defects","year":2009,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Columbian Hospital; University of British Columbia Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Biology; Comparative genomic hybridization; Genetics; Ploidy; Copy-number variation; Embryo; Chromosome; Karyotype; Polyploid; Copy number analysis; Genome; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001591641,0.0001738574,0.0002002364,0.0001577197,0.0001224481,0.0000225664,0.00006752674,0.00008166637,0.00001871167],"category_scores_gemma":[0.00009653352,0.0001638037,0.00003127263,0.00021999,0.00004476801,0.00003696033,0.00001592624,0.0002100109,0.0000112348],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00016144,"about_ca_system_score_gemma":0.00003019884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009766774,"about_ca_topic_score_gemma":0.0001080994,"domain_scores_codex":[0.9987399,0.00004280805,0.0001744035,0.0005633888,0.0002194723,0.0002600186],"domain_scores_gemma":[0.9994344,0.000006001744,0.00007105665,0.0003510007,0.00004856673,0.00008897624],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008121188,0.0001525821,0.006147315,0.0000187169,0.00002105425,0.0001492306,0.0001825815,0.00002480566,0.9889458,0.00004406349,0.0002614974,0.003971105],"study_design_scores_gemma":[0.001219433,0.0008437632,0.2189469,0.00011807,0.00004680481,0.0002346166,0.00005868232,0.000002832129,0.7776719,0.0001313037,0.0005073129,0.0002182816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966186,0.0004606455,0.0005475511,0.0003618376,0.00003666545,0.000435409,0.000001723979,0.000146843,0.001390744],"genre_scores_gemma":[0.997818,0.0000069863,0.00126409,0.0002271838,0.0001152455,0.00002417613,0.0001635877,0.00002595942,0.0003548047],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2127996,"threshold_uncertainty_score":0.667972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01141237078081653,"score_gpt":0.2413577192978209,"score_spread":0.2299453485170044,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}