{"id":"W2127485428","doi":"10.1002/chem.201500476","title":"Acid Chloride Synthesis by the Palladium‐Catalyzed Chlorocarbonylation of Aryl Bromides","year":2015,"lang":"en","type":"article","venue":"Chemistry - A European Journal","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Palladium; Chemistry; Aryl; Catalysis; Reagent; Nucleophile; Steric effects; Reductive elimination; Halogen; Oxidative addition; Chloride; Combinatorial chemistry; Medicinal chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001991984,0.0002751765,0.0002998385,0.00003210433,0.0001771226,0.0001275781,0.000670187,0.00007243565,0.001976351],"category_scores_gemma":[0.002630903,0.0002202735,0.0002064089,0.0002223078,0.0002123377,0.0001603397,0.0001371006,0.0004762382,0.00005202464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001904419,"about_ca_system_score_gemma":0.0002075283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006021688,"about_ca_topic_score_gemma":2.662445e-7,"domain_scores_codex":[0.9979068,0.00007927923,0.0007704288,0.0003030792,0.0006434854,0.0002969177],"domain_scores_gemma":[0.997746,0.000282244,0.0006919877,0.0005958762,0.0003379605,0.0003459169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001997081,0.00006825089,0.0005539451,0.00008944787,0.0001294697,0.00002858073,0.0002559233,0.0001773126,0.9848477,0.000006571858,0.01069489,0.00294821],"study_design_scores_gemma":[0.0008826067,0.000007408294,0.0001738135,0.0001118633,0.0001284003,0.0007777705,0.0005232038,0.0009784565,0.9777853,0.0001138997,0.01826195,0.0002553362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9518028,0.0009113579,0.004957308,0.0005704153,0.0002621685,0.00005498809,0.00007190184,0.00009756959,0.04127145],"genre_scores_gemma":[0.9945093,0.0000607567,0.0006225738,0.00005987947,0.001107077,0.000006443157,0.0001151098,0.00008289109,0.003435943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04270648,"threshold_uncertainty_score":0.998936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03198180704476639,"score_gpt":0.2491444613348575,"score_spread":0.2171626542900912,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}