{"id":"W2127489305","doi":"10.1161/atvb.34.suppl_1.2","title":"Abstract 2: Elucidation of the Mechanism of Apolipoprotein(a)/Lipoprotein(a)-Induced Interleukin 8 Gene Expression: Insight into Potential Receptors and Signaling Pathways and the Role of Oxidized Phospholipids","year":2014,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor","funders":"","keywords":"Apolipoprotein B; Receptor; Signal transduction; TLR2; Secretion; Kringle domain; Biology; Lipoprotein(a); Chemistry; Mutation; Lipoprotein; Biochemistry; Molecular biology; Cell biology; Gene; Recombinant DNA; TLR4; Cholesterol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001546151,0.0004441716,0.0002752292,0.0001317722,0.0001105578,0.0002785783,0.0001970311,0.0003471884,0.004077251],"category_scores_gemma":[0.0001049674,0.00008290116,0.0003205292,0.0001066088,0.0002268278,0.0002719191,0.0001684612,0.0005805912,0.001258729],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002460116,"about_ca_system_score_gemma":0.0002382437,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001777753,"about_ca_topic_score_gemma":0.0001337731,"domain_scores_codex":[0.9999064,0.00001628881,0.000007865119,0.00002625462,0.00001863309,0.00002453355],"domain_scores_gemma":[0.9998995,0.0000190464,0.00002550442,0.00000808596,0.00002543835,0.00002244304],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004715216,0.00006486078,0.0002682537,0.0001473381,0.000004633943,0.0001316857,0.00000989347,0.00004853139,0.9962783,0.0001688647,0.00008804449,0.002318101],"study_design_scores_gemma":[0.00006863373,0.0007573363,0.004975084,0.00002481024,0.00002214302,0.0004615884,0.00003247266,0.0007761035,0.9886426,0.0002163846,0.004018045,0.000004824233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9801778,0.005680279,0.009164853,0.0005853198,0.0002296207,0.00009439167,0.0006391899,0.00007957374,0.00334906],"genre_scores_gemma":[0.9745424,0.004074447,0.007441922,0.0003561267,0.0002256149,0.000113779,0.001437542,0.00003015429,0.01177796],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004077251,"threshold_uncertainty_score":0.01363981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01056337139330645,"score_gpt":0.2040045130192024,"score_spread":0.193441141625896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}