{"id":"W2127496189","doi":"10.1534/g3.111.000836","title":"Genome-wide Fitness Profiles Reveal a Requirement for Autophagy During Yeast Fermentation","year":2011,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"Fermentation and Sensory Analysis","field":"Agricultural and Biological Sciences","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Toronto","keywords":"Saccharomyces cerevisiae; Fermentation; Biology; Yeast; Yeast in winemaking; Fermentation in winemaking; Ribosome biogenesis; Autophagy; Gene; Population; Cell biology; Genetics; Biochemistry; Ribosome; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001312636,0.0002451714,0.0003837861,0.0006156168,0.0002082167,0.0004664533,0.0001262995,0.0002891413,0.0004648024],"category_scores_gemma":[0.0002290217,0.0001443815,0.0003052954,0.0005126626,0.0001561163,0.0001228232,0.0002849833,0.0002390123,0.0001179628],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001774381,"about_ca_system_score_gemma":0.0001113349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001118292,"about_ca_topic_score_gemma":0.001659879,"domain_scores_codex":[0.9998971,0.00001150694,0.00001122316,0.00003250242,0.00002513289,0.00002255385],"domain_scores_gemma":[0.9997706,0.00004994313,0.00007704415,0.00002022042,0.00003738799,0.00004488934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000403652,0.0000230522,0.02848594,0.00002714271,0.00004175798,0.00007208275,0.0000362023,0.0002004779,0.9689802,0.00001922919,0.00003969994,0.001670584],"study_design_scores_gemma":[0.00001103144,0.0002025772,0.880363,0.000005487516,0.00007384482,0.0004423634,0.0001426462,0.001113466,0.1170966,0.00008454401,0.0004456117,0.00001891348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987955,0.0001910029,0.0002383883,0.0000109797,0.000001199834,0.000003333114,0.0006380866,0.00001560337,0.000105916],"genre_scores_gemma":[0.9976744,0.0001276742,0.0003387022,0.00001986955,0.00000128712,0.000006573024,0.001665029,0.00001009136,0.000156275],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001118292,"threshold_uncertainty_score":0.002223611,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05882400385623958,"score_gpt":0.2501619596052588,"score_spread":0.1913379557490192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}