{"id":"W2127539800","doi":"10.1074/jbc.m109.046151","title":"The Human Carnitine Transporter SLC22A16 Mediates High Affinity Uptake of the Anticancer Polyamine Analogue Bleomycin-A5","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":124,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Canadian Institutes of Health Research","keywords":"Bleomycin; Biology; Cancer research; Cancer cell; Polyamine; Transfection; Molecular biology; Cancer; Cell culture; Biochemistry; Chemotherapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000734825,0.0002560445,0.0002405853,0.0001066761,0.0001373228,0.0003331069,0.0001242877,0.0002431735,0.001048971],"category_scores_gemma":[0.00009235321,0.0001222438,0.0001937757,0.0001643857,0.0001366508,0.000139426,0.0001459403,0.000144084,0.0006108948],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003279199,"about_ca_system_score_gemma":0.0002178431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002378445,"about_ca_topic_score_gemma":0.002750176,"domain_scores_codex":[0.9999205,0.00001299607,0.000009249412,0.00002418063,0.00002033454,0.00001264856],"domain_scores_gemma":[0.9999479,0.00000494803,0.00001631189,0.000007601758,0.000007338892,0.00001586009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005356279,0.000007057869,0.0003640551,0.00002854411,0.000003895243,0.00005301809,0.00001033572,0.0000342446,0.9988952,0.00004444396,0.00003397577,0.0004716507],"study_design_scores_gemma":[0.00002245285,0.0001536278,0.008492737,0.000008785824,0.00001610373,0.0006502593,0.00004381703,0.00141435,0.983713,0.00002322682,0.005454684,0.000007014784],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941766,0.001811843,0.00198802,0.0001074106,0.0000211515,0.00002186285,0.0006440288,0.00009896339,0.001130065],"genre_scores_gemma":[0.9930255,0.001173283,0.001398005,0.00003708492,0.000006259956,0.00001417237,0.0008780195,0.00001985437,0.003447755],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002378445,"threshold_uncertainty_score":0.004729211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01107014022280326,"score_gpt":0.2414648071823315,"score_spread":0.2303946669595283,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}